| malic | <chemistry> Pertaining to, or obtained from, apples; as, malic acid. Malic acid, a hydroxy acid obtained as a substance which is sirupy or crystallized with difficulty, and has a strong but pleasant sour taste. It occurs in many fruits, as in green apples, currants, etc. It is levorotatory or dextrorotatory according to the temperature and concentration. An artificial variety is a derivative of succinic acid, but has no action on polarized light, and thus malic acid is a remarkable case of physical isomerism. Origin: L. Malum an apple: cf. F. Malique. Source: Websters Dictionary (01 Mar 1998) |
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| malic acid | HOOC-CH2-CHOH-COOH; hydroxysuccinic acid;an acid found in apples and various other tart fruits; an intermediate in the tricarboxylic acid cycle, the glyoxylate cycle, and in a shuttle system. Synonym: monohydroxysuccinic acid. (05 Mar 2000) |
| malic acid dehydrogenase | <enzyme> An enzyme that catalyses the conversion of (s)-malate and NAD+ to oxaloacetate and NADH. Chemical name: (S)-Malate:NAD+ oxidoreductase Registry number: EC 1.1.1.37 (12 Dec 1998) |
| malic dehydrogenase | <enzyme> An enzyme that catalyses the conversion of (s)-malate and NAD+ to oxaloacetate and NADH. Chemical name: (S)-Malate:NAD+ oxidoreductase Registry number: EC 1.1.1.37 (12 Dec 1998) |
| malic enzyme | <enzyme> An enzyme that catalyses the conversion of (s)-malate and NAD+ to oxaloacetate and NADH. Chemical name: (S)-Malate:NAD+ oxidoreductase Registry number: EC 1.1.1.37 (12 Dec 1998) |
| malice | 1. Enmity of heart; malevolence; ill will; a spirit delighting in harm or misfortune to another; a disposition to injure another; a malignant design of evil. "Nor set down aught in malice." "Envy, hatred, and malice are three distinct passions of the mind." (Ld. Holt) 2. Any wicked or mischievous intention of the mind; a depraved inclination to mischief; an intention to vex, annoy, or injure another person, or to do a wrongful act without just cause or cause or excuse; a wanton disregard of the rights or safety of others; willfulness. Malice aforethought or prepense, malice previously and deliberately entertained. Synonym: Spite, ill will, malevolence, grudge, pique, bitterness, animosity, malignity, maliciousness, rancor, virulence. See Spite. Malevolence, Malignity, Malignancy. Malice is a stronger word than malevolence, which may imply only a desire that evil may befall another, while malice desires, and perhaps intends, to bring it about. Malignity is intense and deepseated malice. It implies a natural delight in hating and wronging others. One who is malignant must be both malevolent and malicious; but a man may be malicious without being malignant. "Proud tyrants who maliciously destroy And ride o'er ruins with malignant joy." (Somerville) "in some connections, malignity seems rather more pertinently applied to a radical depravity of nature, and malignancy to indications of this depravity, in temper and conduct in particular instances." (Cogan) Origin: F. Malice, fr. L. Malitia, from malus bad, ill, evil, prob. Orig, dirty, black; cf. Gr. Black, Skr. Mala dirt. Cf. Mauger. Source: Websters Dictionary (01 Mar 1998) |
| malicious | 1. Indulging or exercising malice; harboring ill will or enmity. "I grant him bloody, . . . Sudden, malicious, smacking of every sin That has a name." (Shak) 2. Proceeding from hatred or ill will; dictated by malice; as, a malicious report; malicious mischief. 3. With wicked or mischievous intentions or motives; wrongful and done intentionally without just cause or excuse; as, a malicious act. Malicious abandonment, the desertion of a wife or husband without just cause. Malicious mischief, a wanton prosecution or arrest, by regular process in a civil or criminal proceeding, without probable cause. Synonym: Ill-disposed, evil-minded, mischievous, envious, malevolent, invidious, spiteful, bitter, malignant, rancorous, malign. Maliciously, Maliciousness. Origin: Of. Malicius, F. Malicieux, fr. L. Malitiosus. See Malice. Source: Websters Dictionary (01 Mar 1998) |
| pyruvic-malic carboxylase | <enzyme> An enzyme that catalyses the conversion of (s)-malate and NAD+ to oxaloacetate and NADH. Chemical name: (S)-Malate:NAD+ oxidoreductase Registry number: EC 1.1.1.37 (12 Dec 1998) |
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