| malate |
A compound formed when a mineral is bound to malic acid.
출처: www.enzy.com/glossary/searchresults.asp
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| malate dehydrogenase |
[EC 1.1.1.37] an enzyme of the oxidoreductase class that catalyzes the oxidation of L-malate to oxaloacetate, reducing NAD+. The enzyme occurs both in the mitochondria and in the cytosol. The reaction is important in the tricarboxylic acid cycle and in the malate-aspartate electron shuttle. See illustration at tricarboxylic acid cycle, under cycle.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of L-malate to form pyruvate, reducing NADP+. The cytosolic and mitochondrial forms are isozymes; the cytosolic enzyme is a major source of NADPH for fatty acid synthesis.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| malate-aspartate s. |
a mechanism for transferring electrons into mitochondria from the cytosol of red fibers of skeletal muscle, heart, and the brain, involving cytosolic and mitochondrial forms of the enzymes malate dehydrogenase and aspartate transaminase, and two transmembrane carriers. Electrons from cytosolic NADH are used to reduce oxaloacetate to malate, which enters the mitochondrial matrix and donates electrons to NAD+, becoming reoxidized to oxaloacetate. To return to the cytosol, oxaloacetate is first transaminated to form aspartate, which can traverse the membrane; once in the cytosol it is deaminated to oxaloacetate.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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