| malarial cachexia | Malaria that develops after frequently repeated attacks of one of the acute forms, usually falciparum malaria; it is characterised by profound anaemia, enlargement of the spleen, emaciation, mental depression, sallow complexion, oedema of ankles, feeble digestion, and muscular weakness. Synonym: limnaemia, malarial cachexia. (05 Mar 2000) |
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| malarial | Pertaining to or affected with malaria. (05 Mar 2000) |
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| malarial crescent | The male or female gametocyte(s) of Plasmodium falciparum, whose presence in human red blood cells is diagnostic of falciparum malaria. Synonym: crescent, sickle form. Myopic crescent, a white or grayish white crescentic area in the fundus of the eye located on the temporal side of the optic disk; caused by atrophy of the choroid, permitting the sclera to become visible. Synonym: myopic conus. Sublingual crescent, the crescent-shaped area on the floor of the mouth formed by the lingual wall of the mandible and the adjacent part of the floor of the mouth. (05 Mar 2000) |
| malarial haemoglobinuria | A condition, now uncommon, resulting from Plasmodium falciparum infection (malignant tertian malaria with severe haemolysis); frequently seen in Caucasians after interrupted treatment with quinine. Synonym: blackwater fever, haemoglobinuric fever, West African fever. (05 Mar 2000) |
| malarial knobs | Rounded protrusions of a red blood cell infected with Plasmodium falciparum, responsible for the adhesion of infected red cells to one another and to the endothelium of the blood vessels containing these infected cells; results in capillary blockage responsible for much of the pathology of malignant tertian malaria. (05 Mar 2000) |
| malarial periodicity | A clinical rhythmicity reflected in periodic fevers and chills recurring at approximately 48-hour intervals in tertian malaria (Plasmodium vivax or P. Ovale) or at 72-hour intervals in quartan malaria (Periodicity malariae); the rhythm of tertian or 48-hour cycles is frequently modified in malignant tertian or falciparum malaria (P. Falciparum); associated with release of merozoites from red cells during erythrocytic schizogony, although the controlling mechanism for the synchronous release is unknown. (05 Mar 2000) |
| malarial pigment | A dark brown, granular pigment which rotates the plane of polarised light and has other properties similar to formalin pigment; occurs in parasites, such as Plasmodium malariae, around brain capillaries, and in fixed macrophages of spleen, liver, bone marrow, and lymph nodes. See: malarial pigment stain. (05 Mar 2000) |
| malarial pigment stain | <technique> A stain using phloxine-toluidine blue O sequence; malarial pigment and nuclei are bluish, erythrocytes and cytoplasm are red to orange; found in phagocytic cells of the reticuloendothelial system. (05 Mar 2000) |
| malignant tertian malarial parasite | A species of protozoa that is the causal agent of falciparum malaria (malaria, falciparum). It is most prevalent in the tropics and subtropics. (12 Dec 1998) |
| intermittent malarial fever | See: intermittent malaria. (05 Mar 2000) |
| cachexia | <oncology> A profound and marked state of constitutional disorder, general ill health and malnutrition. Origin: Gr. Hexis = habit (18 Nov 1997) |
| cachexia aphthosa | <gastroenterology> An inherited disease where the intestinal lining is inflamed in response to the ingestion of a protein known as gluten. Gluten is present in many grains including rye, oats, barley and triticale. Symptoms in infants include diarrhoea, slow growth, bloody stools, weight loss, vomiting and clay-coloured stools. Symptoms in adults include abdominal distention, abdominal pain, fatigue, weight loss, bone pain and bone tenderness. Treatment involves the life-long avoidance of gluten. (04 Mar 1998) |
| cachexia aquosa | An edematous form of ancylostomiasis. Diabetic neuropathic cachexia, a clinical syndrome seen almost exclusively in elderly diabetic males, consisting of the rather sudden onset of severe limb pain, marked weight loss, depression, and impotence. These patients appear to have a combination of a severe diabetic polyneuropathy, diffuse bilateral diabetic polyradiculopathy, and diabetic autonomic neuropathy. (05 Mar 2000) |
| cachexia hypophyseopriva | A condition following total removal of the hypophysis cerebri resulting in panhypopituitarism marked by a fall of body temperature, electrolyte imbalance, and hypoglycaemia, followed by coma and death. (05 Mar 2000) |
| cachexia strumipriva | Signs and symptoms of hypothyroidism (with or without myxoedema) resulting from the loss of thyroid tissue, either from surgery, radiotherapy, or disease. Synonym: cachexia strumipriva, cachexia thyroidea. (05 Mar 2000) |
| cachexia thyroidea | Signs and symptoms of hypothyroidism (with or without myxoedema) resulting from the loss of thyroid tissue, either from surgery, radiotherapy, or disease. Synonym: cachexia strumipriva, cachexia thyroidea. (05 Mar 2000) |