| lytic pathway | The steps in the method that a virus takes to complete a lytic cycle, including the production and assembly of progeny viruses with host cell machinery and the destruction of the host cell by rupturing its plasma membrane (lysis), releasing the progeny viruses in the process. (09 Oct 1997) |
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| Mlt38 lytic transglycosylase | <enzyme> Active against poly(murnac-glcnac) strands Registry number: EC 2.4.- Synonym: membrane-bound lytic transglycosylase 38-kD, mlt38 protein, mlta gene product (26 Jun 1999) |
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| direct lytic factor of cobra venom | A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent. Synonym: cobra toxin, direct lytic factor of cobra venom. (05 Mar 2000) |
| direct lytic factors | most abundant proteins in cobra (naja of the elapids) venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contracture, interferes with neuromuscular and ganglionic transmission, depolarises nerve, muscle and blood cell membranes, thus causing haemolysis. Synonym: cobramine a; cobramine b; cobra cytotoxin; gamma toxin; membrane-active polypeptide. (12 Dec 1998) |
| lytic | 1. Pertaining to lysis or to a lysin. 2. Producing lysis. Origin: Gr. Lysis = dissolution (18 Nov 1997) |
| lytic complex | <immunology> The large (2000 kD) cytolytic complex formed from complement C5b6789. See: complement. (18 Nov 1997) |
| lytic cycle | The general life cycle of a lytic virus, from infection of the host cell, hijacking of the host cells mechanisms, use of the host cells mechanisms to produce viral components, and assembly of the components into progeny viruses, to the destruction of the host cell by rupturing its plasma membrane (lysis) and the release of the progeny viruses so that they can spread and infect other cells. (09 Oct 1997) |
| lytic infection | The normal cycle of infection of a cell by a virus or bacteriophage, in which mature virus or phage particles are produced and the cell is then lysed. (18 Nov 1997) |
| lytic phage | A bacteriophage (virus which infects bacteria) that can only follow the lytic pathway to completing its lytic cycle, and does not have the mechanisms to enter the lysogenic pathway. (09 Oct 1997) |
| lytic phase | A phase of the virus life cycleduring which the virus replicates within the host cell, releasing a new generation of viruses when the infectedcell lyses. (09 Oct 1997) |
| lytic virus | <virology> A virus which, as part of its life cycle, causes its host cells plasma membrane to rupture (to lyse). (09 Oct 1997) |
| alternative oxidase pathway | Pathway of mitochondrial electron transport in higher plants, particularly in fruits and seeds, that does not involve cytochrome oxidase and thus is resistant to cyanide. (18 Nov 1997) |
| alternative pathway | See: complement activation. (18 Nov 1997) |
| anabolic pathway | <biochemistry> A reaction or series of reactions in a metabolic pathway that synthesise complex molecules from simpler ones, usually requiring the input of energy. Compare: catabolic pathway. (09 Oct 1997) |
| auditory pathway | Neural paths and connections within the central nervous system, beginning at the organ of Corti's hair cells, continuing along the eighth nerve, and terminating at the auditory cortex. (05 Mar 2000) |
| GABA pathway | The pathway that ultimately converts 4-aminobutyrate to succinate; succinate is then converted to alpha-ketoglutarate, via the tricarboxylic acid cycle, which is then acted upon by glutamate dehydrogenase; glutamate is then decarboxylated to reform 4-aminobutyrate; an important pathway for those cells which make this neuroactive molecule. Synonym: GABA pathway. (05 Mar 2000) |