| Mlt38 lytic transglycosylase | <enzyme> Active against poly(murnac-glcnac) strands Registry number: EC 2.4.- Synonym: membrane-bound lytic transglycosylase 38-kD, mlt38 protein, mlta gene product (26 Jun 1999) |
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| direct lytic factor of cobra venom | A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent. Synonym: cobra toxin, direct lytic factor of cobra venom. (05 Mar 2000) |
| direct lytic factors | most abundant proteins in cobra (naja of the elapids) venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contracture, interferes with neuromuscular and ganglionic transmission, depolarises nerve, muscle and blood cell membranes, thus causing haemolysis. Synonym: cobramine a; cobramine b; cobra cytotoxin; gamma toxin; membrane-active polypeptide. (12 Dec 1998) |
| lytic | 1. Pertaining to lysis or to a lysin. 2. Producing lysis. Origin: Gr. Lysis = dissolution (18 Nov 1997) |
| lytic complex | <immunology> The large (2000 kD) cytolytic complex formed from complement C5b6789. See: complement. (18 Nov 1997) |
| lytic cycle | The general life cycle of a lytic virus, from infection of the host cell, hijacking of the host cells mechanisms, use of the host cells mechanisms to produce viral components, and assembly of the components into progeny viruses, to the destruction of the host cell by rupturing its plasma membrane (lysis) and the release of the progeny viruses so that they can spread and infect other cells. (09 Oct 1997) |
| lytic infection | The normal cycle of infection of a cell by a virus or bacteriophage, in which mature virus or phage particles are produced and the cell is then lysed. (18 Nov 1997) |
| lytic pathway | The steps in the method that a virus takes to complete a lytic cycle, including the production and assembly of progeny viruses with host cell machinery and the destruction of the host cell by rupturing its plasma membrane (lysis), releasing the progeny viruses in the process. (09 Oct 1997) |
| lytic phage | A bacteriophage (virus which infects bacteria) that can only follow the lytic pathway to completing its lytic cycle, and does not have the mechanisms to enter the lysogenic pathway. (09 Oct 1997) |
| lytic phase | A phase of the virus life cycleduring which the virus replicates within the host cell, releasing a new generation of viruses when the infectedcell lyses. (09 Oct 1997) |
| lytic virus | <virology> A virus which, as part of its life cycle, causes its host cells plasma membrane to rupture (to lyse). (09 Oct 1997) |
| acetyl-activating enzyme | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acyl-activating enzyme | <enzyme> Fatty acid thiokinase (long-chain), a ligase forming acyl-CoA, AMP, and pyrophosphate from long-chain fatty acids, ATP, and coenzyme A. Activity is independent of phosphatidylcholine Registry number: EC 6.2.1.3 Synonym: acyl-activating enzyme, dodecanoyl-CoA synthetase, fatty acid thiokinase (long chain), acid-coenzyme a ligase, fatty acid-CoA ligase, acyl-CoA synthetase, acyl-CoA ligase, coash ligase, ciprofibroyl-CoA synthetase, pristanoyl-CoA synthetase, palmityl CoA synthetase, palmitoyl CoA synthetase, palmitoyl CoA ligase, fatty acyl-CoA synthetase, very long chain fatty acid acyl-CoA synthetase, vlcfa acyl-CoA synthetase, nafenopin-CoA ligase, palmitoyl-CoA synthase, faa2 gene product, faa2p protein, vlacs enzyme (26 Jun 1999) |
| adaptive enzyme | Inducible enzyme, an enzyme that can be detected in a growing culture of a microorganism, after the addition of a particular substance (inducer) to the culture medium, but was not detectable prior to the addition and can act on the inducer. A prototype is the beta-galactosidase of Escherichia coli, synthesised upon the addition of various galactosides, whether or not these are good substrates. Compare: constitutive enzyme. Synonym: adaptive enzyme. (05 Mar 2000) |
| allosteric enzyme | <biochemistry, chemistry> A regulatory enzyme whose activity is modified by the noncovalent binding of a particular metabolite at a site (the allosteric site) other than the active site. (09 Oct 1997) |