| lysyl hydroxylase | <enzyme> An enzyme that acts on specific lysyl residues in certain proteins (e.g., collagens) with alpha-ketoglutarate and O2 to produce d-hydroxylysyl residues, succinate, and CO2; this enzyme, which requires Fe2+ and ascorbate, is deficient in Ehlers-Danlos syndrome type VI. Synonym: lysyl 2-oxoglutarate dioxygenase. (05 Mar 2000) |
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| lysyl | The univalent radical of lysine. (05 Mar 2000) |
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| lysyl 2-oxoglutarate dioxygenase | <enzyme> An enzyme that acts on specific lysyl residues in certain proteins (e.g., collagens) with alpha-ketoglutarate and O2 to produce d-hydroxylysyl residues, succinate, and CO2; this enzyme, which requires Fe2+ and ascorbate, is deficient in Ehlers-Danlos syndrome type VI. Synonym: lysyl 2-oxoglutarate dioxygenase. (05 Mar 2000) |
| lysyl-bradykinin | <protein> Decapeptide (lysyl bradykinin, amino acid sequence KRPPGFSPFR) produced in kidney. Like bradykinin, an inflammatory mediator (a kinin), causes dilation of renal blood vessels and increased water excretion. (18 Nov 1997) |
| lysyl endopeptidase | <enzyme> Alkaline protease with bacteriolytic acitvity from achromobacter lyticus; cleaves carboxyl bond of lysine residues Registry number: EC 3.4.21.50 Synonym: achromobacter protease I, achromopeptidase, lysyl endoprotease (26 Jun 1999) |
| lysyl oxidase | <enzyme> Extracellular enzyme that deaminates lysine and hydroxylysine residues in collagen or elastin to form aldehydes, that then interact with each other or with other lysyl side chains to form crosslinks. (18 Nov 1997) |
| abscisic acid 8'-hydroxylase | <enzyme> Catalyses conversion of abscisic acid to 8'-hydroxyabscisic acid, which rearranges to phaseic acid Registry number: EC 1.14.99.- Synonym: aba 8'-hydroxylase (26 Jun 1999) |
| aflatoxin B1 hydroxylase | <enzyme> Hydroxylases may be replaced by mixed function oxidases as appropriate Registry number: EC 1.14.- Synonym: aflatoxin b1 4-hydroxylase (26 Jun 1999) |
| aklavinone 11-hydroxylase | <enzyme> A flavin-type bacterial hydroxylase from streptomyces peucetius; 489 amino acid residues, mw 52.3 kD; genbank u09844 Registry number: EC 1.14.14.- Synonym: dnrf protein, dnrf gene product (26 Jun 1999) |
| aniline hydroxylase | <enzyme> A drug-metabolizing, cytochrome p-450 enzyme which catalyses the hydroxylation of aniline to hydroxyaniline in the presence of reduced flavoprotein and molecular oxygen. Registry number: EC 1.14.14.- (12 Dec 1998) |
| arachidonic acid 18-hydroxylase | <enzyme> Converts arachidonic acid to 18-hydroxy-5,8,11,14-eicosatetraenoic acid in the presence of NADPH; cytochrome p450 enzyme Registry number: EC 1.14.13.- Synonym: arachidonic acid 18(r)-hydroxylase, arachidonic acid omega 3-hydroxylase (26 Jun 1999) |
| arylamine N-hydroxylase | <enzyme> Cytochrome p-448 dependent Registry number: EC 1.14.13.- Synonym: 2-aminofluorene n-hydroxylase (26 Jun 1999) |
| benzopyrene hydroxylase | <enzyme> A drug-metabolizing, cytochrome p-448 (p-450) enzyme which catalyses the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. Registry number: EC 1.14.14.- (12 Dec 1998) |
| beta-carotene hydroxylase | <enzyme> O2-dependent NADPH-dependent monooxygenase from erwinia herbicola; forms zeaxanthin; amino acid sequence has been determined; genbank m87280 Registry number: EC 1.14.13.- Synonym: beta-carotene monooxygenase, crtz gene product (26 Jun 1999) |
| biphenyl-4-hydroxylase | <enzyme> Mixed function oxidase Registry number: EC 1.14.14.- (26 Jun 1999) |
| bufuralol 1'-hydroxylase | <enzyme> Liver microsomal enzyme utilizing NADPH and cytochrome p-450; competetive inhibition by debrisoquine Registry number: EC 1.14.99.- Synonym: bufuralol 1'-monooxygenase (26 Jun 1999) |