| lymphoma, diffuse | Malignant lymphoma in which neoplastic cells diffusely infiltrate the entire lymph node without any definite organised pattern. Patients whose lymphomas present a diffuse pattern generally have a more unfavorable survival outlook than those presenting with a follicular or nodular pattern. (12 Dec 1998) |
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| diffuse small cleaved cell lymphoma | <tumour> A diffuse poorly differentiated lymphocytic lymphoma; follicular centre cell lymphoma that lacks a follicular pattern; malignancy is of intermediate grade. (05 Mar 2000) |
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| lymphoma, large-cell, diffuse | Malignant lymphoma composed of large cells which may be both cleaved and noncleaved. The pattern is predominantly diffuse. most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. (12 Dec 1998) |
| lymphoma, mixed-cell, diffuse | A heterogeneous group of intermediate-grade lymphomas of mixed cellular composition. Although they have not been extensively studied, it appears that they are predominantly B-cell diseases. (12 Dec 1998) |
| lymphoma, small cleaved-cell, diffuse | An intermediate-grade malignant lymphoma in which the neoplastic cells (B-lymphocytes) exhibit variability in size, configuration, and degree of differentiation. The cells have distinctive nuclei, irregular in shape, with marked indentations and angularity. (12 Dec 1998) |
| cerebral sclerosis, diffuse | Diffuse progressive degeneration of the white matter of the brain, accompanied by mental deterioration, severe motor disturbances, and early death. (12 Dec 1998) |
| goiter, diffuse toxic | Graves' disease, the most common cause of hyperthroidism, too much thyroid hormone. (12 Dec 1998) |
| chronic diffuse sclerosing osteomyelitis | A proliferative reaction of bone to a low-grade infection of the jaws; most often seen in middle-aged or older black women as extensive, often bilateral radio-opacities of the mandible and maxilla. (05 Mar 2000) |
| hyperostosis, diffuse idiopathic skeletal | A disease of elderly men characterised by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions. (12 Dec 1998) |
| diffuse | Not definitely limited or localised, widely distributed. Origin: L. Dis = apart, fundere = to pour (18 Nov 1997) |
| diffuse abdominal calcification | <radiology> Ovarian cystadenocarcinoma (psammomatous Calcium), pseudomyxoma peritonei, pseudomucinous cystadenoma of ovary, mucocele of appendix, undifferentiated abdominal malignancy, TB peritonitis, oil granulomata, meconium peritonitis (12 Dec 1998) |
| diffuse abscess | A collection of pus not circumscribed by a well-defined capsule. (05 Mar 2000) |
| diffuse aneurysm | An aneurysm that has enlarged and spread to the surrounding tissues in consequence of rupture of its walls. Synonym: consecutive aneurysm. (05 Mar 2000) |
| diffuse angiokeratoma | <disease> Lysosomal storage disease caused by a deficiency of alpha-galactosidase a and resulting in an accumulation of globotriaosylceramide in the renal and cardiovascular systems. The disease is characterised by telangiectatic skin lesions, renal failure, and disturbances of the cardiovascular, gastrointestinal, and central nervous systems. Inheritance: x-linked. (08 Mar 2000) |
| diffuse arterial ectasia | Spontaneous enlargement with dilation of the vessels in a circumscribed area. (05 Mar 2000) |
| diffuse brain atrophy | A form of dementia caused by destruction (atrophy) of the frontal lobes of the brain. This condition leads to the progressive deterioration of mental functioning. Incidence: 9 in 10,000 people in the general population. (27 Sep 1997) |