| acromegalic gigantism | A form of pituitary gigantism in which the signs of acromegaly accompany abnormal height. (05 Mar 2000) |
|---|---|
| gigantism | A condition where there is over-production of growth hormone by the pituitary gland in a child before the bone growth plates close, resulting in excessive long bone growth. (27 Sep 1997) |
| cerebral gigantism | A syndrome characterised by increased birth weight and length (above 90th percentile), accelerated growth rate for the first 4 or 5 years without elevation of serum growth hormone levels, and then reversion to normal growth rate; characteristic facies include prognathism, hypertelorism, antimongoloid slant, and dolichocephalic skull; moderate mental retardation and impaired coordination are also associated. See: Sotos' syndrome. (05 Mar 2000) |
| pituitary gigantism | Excessive growth due to overactivity of the pituitary gland (specifically of the anterior pituitary). (12 Dec 1998) |
| primordial gigantism | Unusually large size from birth due to familial or genetic factors or intrauterine environment (e.g., maternal prediabetic state) and not to hyperpituitarism. (05 Mar 2000) |
| eunuchoid gigantism | Gigantism with deficient development of sexual organs; may be of pituitary or gonadal origin; gigantism accompanied by body proportions typical of hypogonadism during adolescence. (05 Mar 2000) |
| focal gigantism | <radiology> Neurofibromatosis, AVM, Klippel-Trenaunay-Weber syndrome, Beckwith-Wiedemann syndrome, Parks-Davis syndrome, haemangioma, JRA (12 Dec 1998) |
| foetal gigantism | Excessive foetal or newborn size, e.g., cerebral gigantism and infants of diabetic mothers. (05 Mar 2000) |
| anaesthesia, local | Anaesthesia confined to one part of the body. Infiltration anaesthesia produces local anaesthesia by deposition of a local anaesthesia solution in the area of small, terminal nerve endings. (12 Dec 1998) |
| anaesthetics, local | Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fibre. In contact with a nerve trunk, these anaesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. Nearly all local anaesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. They are commonly used not only in the peripheral nervous system, but also for spinal anaesthesia. The many drugs that have local anaesthetic actions as a side effect but are not used for their local anaesthetic action are not included here. (12 Dec 1998) |
| anti-infective agents, local | Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from disinfectants, which are used on inanimate objects. (12 Dec 1998) |
| neoplasm recurrence, local | The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site. (12 Dec 1998) |
| local | Restricted to or pertaining to one spot or part, not general. Origin: L. Localis (18 Nov 1997) |
| local anaemia | Anaemia resulting from a decreased supply of blood to a part, as in the occlusion of a vessel. (05 Mar 2000) |
| local anaesthesia | The use of a local anaesthetic (usually injected into the tissue) results in a small region of anaesthesia (numbness). Lidocaine (Xylocaine) or (Marcaine) are commonly used. Origin: Gr. Aisthesis = sensation (27 Sep 1997) |