| lipoxygenase | <enzyme> Enzyme that catalyses the oxidative conversion of arachidonic acid to the hydroxyeicosenoic acid (HETE) structure in the synthesis of leucotrienes. (18 Nov 1997) |
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| lipoxygenase inhibitors | Compounds or agents that combine with lipoxygenase and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of the eicosanoid products hydroxyeicosatetraenoic acid and various leukotrienes. (12 Dec 1998) |
| arachidonate 12-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-hpete) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-hete). The 12-hydroperoxides are preferentially formed in platelets. Chemical name: Arachidonate:oxygen 12-oxidoreductase Registry number: EC 1.13.11.31 (12 Dec 1998) |
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| arachidonate 15-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-hpete) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-hete). The 15-hydroperoxides are preferentially formed in neutrophils and lymphocytes. Chemical name: Arachidonate:oxygen 15-oxidoreductase Registry number: EC 1.13.11.33 (12 Dec 1998) |
| arachidonate 5-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-hpete) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-hete). The 5-hydroperoxides are preferentially formed in leukocytes. Chemical name: Arachidonate:oxygen 5-oxidoreductase Registry number: EC 1.13.11.34 (12 Dec 1998) |
| arachidonate 8-lipoxygenase | <enzyme> From sea whip coral plexaura homomalla; catalyses the conversion of arachidonic acid to a cyclised prostanoid with a pga ring and the same side chains as the parent arachidonate Registry number: EC 1.13.11.40 Synonym: 8(r)-lipoxygenase, 8-lipoxygenase (26 Jun 1999) |
| 11-lipoxygenase | <enzyme> Sea urchin egg enzyme converts arachidonic acid to 11(r)-hydroperoxyeicosapentaenoic acid Registry number: EC 1.13.11.- Synonym: (11r)-lipoxygenase (26 Jun 1999) |