leukotriene : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 1

Leukotriene A4 - 새창 (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Synonyms : Leukotriene A, Leukotriene A-4, Leukotrienes A, Leukotriene A 4
Leukotriene Antagonists - 새창 A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
Synonyms : Antagonists, Leukotriene, Receptor Antagonists, Leukotriene, Antagonists, Leukotriene Receptor
Leukotriene B4 - 새창 The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
Synonyms : Leukotriene B, Leukotriene B-4, Leukotrienes B, 5, 12 HETE, 5, 12 diHETE, B-4, Leukotriene, Leukotriene B 4
Leukotriene C4 - 새창 The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Synonyms : Leukotriene C, Leukotriene C-1, Leukotriene C-4, Leukotriene C1, Leukotrienes C, Leukotriene C 1, Leukotriene C 4
Leukotriene D4 - 새창 One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Synonyms : Leukotriene D, Leukotriene D-4, Leukotrienes D, Leukotriene D 4