| leukoencephalitis | Encephalitis restricted to the white matter. (05 Mar 2000) |
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| leukoencephalitis, acute haemorrhagic | A rare, fatal postinfection or allergic demyelinating disease of the central nervous system having a fulminating course and occurring mainly in young adults. It is characterised by destruction of white matter to the point of liquefaction; widespread necrosis of blood vessel walls leading to the formation of multiple small haemorrhages in the involved areas and the exudation of fibrin into the surrounding tissue; and cellular infiltration of the necrotic areas. (12 Dec 1998) |
| acute epidemic leukoencephalitis | A disease characterised by acute onset of fever, followed by convulsions, delirium, and coma, and associated with perivascular demyelination and haemorrhagic foci in the central nervous system. Synonym: acute primary haemorrhagic meningoencephalitis, Strumpell's disease. (05 Mar 2000) |
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| acute haemorrhagic leukoencephalitis | A fulminating demyelinating disorder of the central nervous system that affects mainly children and young adults. Almost always preceded by a respiratory infection, characterised by the abrupt onset of fever, headache, confusion, and nuchal rigidity, soon followed by focal seizures, hemiplegia, or quadriplegia, brainstem findings, and coma; the CSF shows evidence of an inflammatory process; due to the massive destruction of the white matter of one or both hemispheres, often accompanied by similar destruction of the white matter of the brainstem and cerebellar peduncles; of unknown aetiology. Synonym: acute haemorrhagic leukoencephalitis, acute necrotizing haemorrhagic leukoencephalitis. (05 Mar 2000) |
| acute necrotizing haemorrhagic leukoencephalitis | A fulminating demyelinating disorder of the central nervous system that affects mainly children and young adults. Almost always preceded by a respiratory infection, characterised by the abrupt onset of fever, headache, confusion, and nuchal rigidity, soon followed by focal seizures, hemiplegia, or quadriplegia, brainstem findings, and coma; the CSF shows evidence of an inflammatory process; due to the massive destruction of the white matter of one or both hemispheres, often accompanied by similar destruction of the white matter of the brainstem and cerebellar peduncles; of unknown aetiology. Synonym: acute haemorrhagic leukoencephalitis, acute necrotizing haemorrhagic leukoencephalitis. (05 Mar 2000) |
| sclerosing leukoencephalitis | <neurology> Chronic progressive illness seen in children a few years after measles infection and involving demyelination of the cerebral cortex. Virus apparently persists in brain cells: usually considered a slow virus disease. (18 Nov 1997) |
| subacute sclerosing leukoencephalitis | <neurology> Chronic progressive illness seen in children a few years after measles infection and involving demyelination of the cerebral cortex. Virus apparently persists in brain cells: usually considered a slow virus disease. (18 Nov 1997) |