| C-terminal leucine protein methyltransferase | <enzyme> Reversibly modifies protein phosphatase 2a by methyl esterification at its c-terminal leucine residues Registry number: EC 2.1.1.- Synonym: tlp methyltransferase (26 Jun 1999) |
|---|---|
| dual leucine zipper bearing kinase | <enzyme> A serine/threonine kinase but hybrid between microtubule-associated protein kinase kinase kinases and the fibroblast growth factor receptor family; genbank u14636; do not confuse with the neoplasm protein dlk Registry number: EC 2.7.10.- Synonym: dlk kinase (26 Jun 1999) |
| enkephalin, leucine | <chemical> Tyrosylglycylglycylphenylalanylleucine. Endogenous pentapeptide with morphine-like activity. The amino acid in position 5 is leucine. Chemical name: L-Leucine, N-(N-(N-(N-L-tyrosylglycyl)glycyl)-L-phenylalanyl)- (12 Dec 1998) |
| enkephalin, leucine-2-alanine | <chemical> N-(n-(n-(n-l-tyrosyl-d-alanyl)glycyl)-l-phenylalanyl)-d-leucine. A synthetic delta-selective opioid peptide with analgesic properties. Treatment with dadle results in transient depression of mean arterial blood pressure and heart rate. Chemical name: D-Leucine, N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)- (12 Dec 1998) |
| leucine | <amino acid> The most abundant amino acid found in proteins. Confers hydrophobicity and has a structural rather than a chemical role. (18 Nov 1997) |
| leucine 2,3-aminomutase | <enzyme> Leucine is converted to 3-amino-4-methylpentanoate (beta leucine) Registry number: EC 5.4.3.7 (26 Jun 1999) |
| leucine acetyltransferase | <enzyme> Forms acetyl-l-leucine from acetyl-CoA plus leucine Registry number: EC 2.3.1.- Synonym: leucine acyltransferase (26 Jun 1999) |
| leucine aminopeptidase | <enzyme> An exopeptidase that removes neutral amino acid residues from the N terminus of proteins. (18 Nov 1997) |
| leucine dehydrogenase | <enzyme> An enzyme that catalyses the reaction of l-leucine, water, and NAD+ to produce NADH, ammonia, and 4-methyl-2-oxopentanoate; used in the treatment of certain tumours. (05 Mar 2000) |
| leucine hypoglycaemia | Reduction in blood glucose concentration produced by administration of leucine; believed to reflect the ability of this amino acid to stimulate insulin secretion. (05 Mar 2000) |
| leucine-induced hypoglycaemia | Rare cause of hypoglycaemia occurring following ingestion of leucine. Seen especially in infants. (05 Mar 2000) |
| leucine-trna ligase | <enzyme> An enzyme that activates leucine with its specific transfer RNA. Chemical name: L-Leucine:tRNA(Leu) ligase (AMP-forming) Registry number: EC 6.1.1.4 (12 Dec 1998) |
| leucine zipper | <molecular biology> Motif found in certain DNA binding proteins. In a region of approximately 35 amino acids, every seventh is a leucine. This facilitates dimerisation of two such proteins to form a functional transcription factor. Examples of proteins containing leucine zippers are products of the proto-oncogenes myc, fos and jun. (15 Oct 1997) |
| leucine zippers | Domains in DNA-binding proteins that contain amino acid sequences that show periodic arrays of leucine residues. These residues exist in an alpha-helical conformation, with the leucine side chains extending from one alpha helix interdigitating with those displayed from a similar alpha helix of a second polypeptide, facilitating dimerization. (12 Dec 1998) |
| acquired sensitivity | 1. <immunology> A state of hypersensitivity induced by exposure to a particular antigen (allergen) resulting in harmful immunologic reactions on subsequent exposures, the term is usually used to refer to hypersensitivity to an environmental antigen (atopic allergy or contact dermatitis) or to drug allergy. The original meaning, now obsolete, included all states of altered immunologic reactivity, immunity as well as hypersensitivity. Gell and Coombs used the term allergic reaction to mean any harmful immunologic reaction causing tissue injury. 2. <study> The medical specialty dealing with diagnosis and treatment of allergic disorders. (18 Nov 1997) |