| LC | Laennec cirrhosis; Langerhans cell; late clamped; large chromophobe; lecithin cholesterol acyltransf... |
|---|---|
| LCAT | lecithin cholesterol acyltransferase |
| DHAP-AT | dihydroxyacetone phosphate acyltransferase |
| LAT | lateral; latex agglutination test; left atrial thrombus; lysolecithin acyltransferase |
| LCAT | Lecithin Cholesterol Acyl-Transferase |
| ACAT | Acyl CoA: Cholesterol-O-acyltransferase |
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| ARAT | Acyl CoA:retinol acyltransferase |
| AT | Acyltransferase |
| DGAT | Diacylglycerol acyltransferase |
| GPAT | Glycerol 3-phosphate acyltransferase |
| lecithin acyltransferase | <enzyme> An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesterol ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anaemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish-eye disease. Synonym: lecithin acyltransferase. Acronym: LCAT (05 Mar 2000) |
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| lecithin acyltransferase deficiency | A disease characterised by deficiency or low levels of plasma lecithin cholesterol acyl transferase. Clinical manifestations include corneal opacity, anaemia, and proteinuria. (12 Dec 1998) |
| lecithin-cholesterol acyltransferase | <enzyme> An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesterol ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anaemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish-eye disease. Synonym: lecithin acyltransferase. Acronym: LCAT (05 Mar 2000) |
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| lecithin-retinol acyltransferase | <enzyme> Transfers 1-acyl moiety from lecithin to retinol-cellular retinol-binding protein, type II, to produce retinyl esters; does not use CoA Registry number: EC 2.3.1.- (26 Jun 1999) |
| lysolecithin-lecithin acyltransferase | <enzyme> An enzyme that catalyses the reversible reaction of lysolecithin and another phospholipid (e.g., phosphatidylethanolamine) to form lecithin and lysophosphatidylethanolamine; a major route in the restructuring of lecithin. (05 Mar 2000) |
| lecithin | <protein> Phospholipids of egg yolk (usually hen's eggs). A mixture of phosphatidylcholine and phosphatidylethanolamine, but usually refers to phosphatidylcholine. (18 Nov 1997) |
| lecithin-cholesterol transferase | A plasma enzyme that catalyses the uptake of cholesterol esters by intermediate-density lipoproteins formed by high density lipoproteins. (05 Mar 2000) |
| lecithin/sphingomyelin ratio | A ratio used to determine foetal pulmonary maturity, found by testing the amniotic fluid; when the lungs are mature, lecithin exceeds sphingomyelin by 2 to 1. (05 Mar 2000) |
| acetyl-CoA acyltransferase | <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation. See: acetyl-CoA acetyltransferase. Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase. (05 Mar 2000) |
| acetyl-CoA c-acyltransferase | <enzyme> Enzyme that catalyses the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Chemical name: Acyl-CoA:acetyl-CoA C-acyltransferase Registry number: EC 2.3.1.16 (12 Dec 1998) |
| acyl-(acyl-carrier-protein)-phospholipid acyltransferase | <enzyme> Catalyses the formation of phosphatidylethanolamine from acyl-acyl carrier protein and 2-acyl-sn-glycero-3-phosphoethanolamine Registry number: EC 2.3.1.40 Synonym: 2-acyl-gpe acyltransferase, 2-acylglycerophosphoethanolamine acyltransferase (26 Jun 1999) |
| acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase | <enzyme> E coli enzyme involved in lipid a biosynthesis; uses beta-hydroxymyristoyl-acyl carrier protein to form udp-3-monoacyl-n-acetylglucosamine; amino acid sequence given in second source Registry number: EC 2.3.1.129 Synonym: udp-aguatransferase, lpxa protein, udp-n-acetylglucosamine-3-acyltransferase, udp-n-acetylglucosamine 3-o-acyltransferase, udp-3-o-(r-3-hydroxymyristoyl)glucosamine-n-acyltransferase, lpxd protein, fira gene product, fira protein (26 Jun 1999) |
| acyl-CoA-1-O-alkyl-2-acetyl-sn-glycerol acyltransferase | <enzyme> From hl-60 cells; related to platelet-activating factor metabolism Registry number: EC 2.3.1.- Synonym: acyl-CoA-1-o-hexadecyl-2-acetyl-sn-glycerol acyltransferase, acaag-acyltransferase, acyl-coenzyme a-1-o-alkyl-2-acetyl-sn-glycerol acyltransferase (26 Jun 1999) |
| acyl-CoA-6-aminopenicillanic acid acyltransferase | <enzyme> Acyl CoA and aminopenicillanic acid yield penicillin and CoA Registry number: EC 2.3.1.- Synonym: 6-apa acyltransferase, 6-aminopenicillanic acid-phenacetyl-CoA-phenoxyacetyl-CoA transferase, acyl-coenzyme a-6-aminopenicillanic acid acyltransferase, isopenicillin n-phenylacetyl-CoA acyltransferase, penicillin acyltransferase, isopenicillin n-phenylacetyl-coenzyme a acyltransferase, acyl-CoA-ipn acyltransferase, isopenicillin n acyltransferase, aat gene product, pende gene product (26 Jun 1999) |
| acyl-CoA-estradiol-17-beta-acyltransferase | <enzyme> Catalyses the esterification of estradiol with long chain fatty acids at the 17-position Registry number: EC 2.3.1.- Synonym: acylcoenzyme a-estradiol-17-beta-acyltransferase, estradiol 17-acyltransferase (26 Jun 1999) |
| acyl-CoA sterol acyltransferase | <enzyme> Isolated from saccharomyces cerevisiae; sat1 and sat2 are isoenzymes; genbank u55383 Registry number: EC 2.3.1- Synonym: sat1 gene product, sat2 gene product (26 Jun 1999) |
| acyl-CoA triterpene acyltransferase | <enzyme> Catalyses the esterification of triterpenes with a fatty acid; requires either acetyl-CoA, ATP, and fatty acid, or fatty acyl-CoA alone Registry number: EC 2.3.1.- Synonym: actt-acyltransferase (26 Jun 1999) |
Synonyms : Deficiency, Lecithin Acyltransferase, Dyslipoproteinemic Corneal Dystrophy, Fish-Eye Disease, LCAT Deficiency, Lecithin:Cholesterol Acyltransferase Deficiency, alpha-LCAT Deficiency, alpha-Lecithin-Cholesterol Acyltransferase Deficiency, Fish Eye Disease
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