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    cholesterol acyl transferase
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LC Laennec cirrhosis; Langerhans cell; late clamped; large chromophobe; lecithin cholesterol acyltransf...
LCAT lecithin cholesterol acyltransferase
DHAP-AT dihydroxyacetone phosphate acyltransferase
LAT lateral; latex agglutination test; left atrial thrombus; lysolecithin acyltransferase
LCAT Lecithin Cholesterol Acyl-Transferase
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
ACAT Acyl CoA: Cholesterol-O-acyltransferase
ARAT Acyl CoA:retinol acyltransferase
AT Acyltransferase
DGAT Diacylglycerol acyltransferase
GPAT Glycerol 3-phosphate acyltransferase
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CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 2 ÆäÀÌÁö: 1
lecithin acyltransferase <enzyme> An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesterol ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anaemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish-eye disease.
Synonym: lecithin acyltransferase.
Acronym: LCAT
(05 Mar 2000)
lecithin acyltransferase deficiency A disease characterised by deficiency or low levels of plasma lecithin cholesterol acyl transferase. Clinical manifestations include corneal opacity, anaemia, and proteinuria.
(12 Dec 1998)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
lecithin-cholesterol acyltransferase <enzyme> An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesterol ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anaemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish-eye disease.
Synonym: lecithin acyltransferase.
Acronym: LCAT
(05 Mar 2000)
lecithin-retinol acyltransferase <enzyme> Transfers 1-acyl moiety from lecithin to retinol-cellular retinol-binding protein, type II, to produce retinyl esters; does not use CoA
Registry number: EC 2.3.1.-
(26 Jun 1999)
lysolecithin-lecithin acyltransferase <enzyme> An enzyme that catalyses the reversible reaction of lysolecithin and another phospholipid (e.g., phosphatidylethanolamine) to form lecithin and lysophosphatidylethanolamine; a major route in the restructuring of lecithin.
(05 Mar 2000)
lecithin <protein> Phospholipids of egg yolk (usually hen's eggs). A mixture of phosphatidylcholine and phosphatidylethanolamine, but usually refers to phosphatidylcholine.
(18 Nov 1997)
lecithin-cholesterol transferase A plasma enzyme that catalyses the uptake of cholesterol esters by intermediate-density lipoproteins formed by high density lipoproteins.
(05 Mar 2000)
lecithin/sphingomyelin ratio A ratio used to determine foetal pulmonary maturity, found by testing the amniotic fluid; when the lungs are mature, lecithin exceeds sphingomyelin by 2 to 1.
(05 Mar 2000)
acetyl-CoA acyltransferase <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation.
See: acetyl-CoA acetyltransferase.
Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase.
(05 Mar 2000)
acetyl-CoA c-acyltransferase <enzyme> Enzyme that catalyses the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
Chemical name: Acyl-CoA:acetyl-CoA C-acyltransferase
Registry number: EC 2.3.1.16
(12 Dec 1998)
acyl-(acyl-carrier-protein)-phospholipid acyltransferase <enzyme> Catalyses the formation of phosphatidylethanolamine from acyl-acyl carrier protein and 2-acyl-sn-glycero-3-phosphoethanolamine
Registry number: EC 2.3.1.40
Synonym: 2-acyl-gpe acyltransferase, 2-acylglycerophosphoethanolamine acyltransferase
(26 Jun 1999)
acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase <enzyme> E coli enzyme involved in lipid a biosynthesis; uses beta-hydroxymyristoyl-acyl carrier protein to form udp-3-monoacyl-n-acetylglucosamine; amino acid sequence given in second source
Registry number: EC 2.3.1.129
Synonym: udp-aguatransferase, lpxa protein, udp-n-acetylglucosamine-3-acyltransferase, udp-n-acetylglucosamine 3-o-acyltransferase, udp-3-o-(r-3-hydroxymyristoyl)glucosamine-n-acyltransferase, lpxd protein, fira gene product, fira protein
(26 Jun 1999)
acyl-CoA-1-O-alkyl-2-acetyl-sn-glycerol acyltransferase <enzyme> From hl-60 cells; related to platelet-activating factor metabolism
Registry number: EC 2.3.1.-
Synonym: acyl-CoA-1-o-hexadecyl-2-acetyl-sn-glycerol acyltransferase, acaag-acyltransferase, acyl-coenzyme a-1-o-alkyl-2-acetyl-sn-glycerol acyltransferase
(26 Jun 1999)
acyl-CoA-6-aminopenicillanic acid acyltransferase <enzyme> Acyl CoA and aminopenicillanic acid yield penicillin and CoA
Registry number: EC 2.3.1.-
Synonym: 6-apa acyltransferase, 6-aminopenicillanic acid-phenacetyl-CoA-phenoxyacetyl-CoA transferase, acyl-coenzyme a-6-aminopenicillanic acid acyltransferase, isopenicillin n-phenylacetyl-CoA acyltransferase, penicillin acyltransferase, isopenicillin n-phenylacetyl-coenzyme a acyltransferase, acyl-CoA-ipn acyltransferase, isopenicillin n acyltransferase, aat gene product, pende gene product
(26 Jun 1999)
acyl-CoA-estradiol-17-beta-acyltransferase <enzyme> Catalyses the esterification of estradiol with long chain fatty acids at the 17-position
Registry number: EC 2.3.1.-
Synonym: acylcoenzyme a-estradiol-17-beta-acyltransferase, estradiol 17-acyltransferase
(26 Jun 1999)
acyl-CoA sterol acyltransferase <enzyme> Isolated from saccharomyces cerevisiae; sat1 and sat2 are isoenzymes; genbank u55383
Registry number: EC 2.3.1-
Synonym: sat1 gene product, sat2 gene product
(26 Jun 1999)
acyl-CoA triterpene acyltransferase <enzyme> Catalyses the esterification of triterpenes with a fatty acid; requires either acetyl-CoA, ATP, and fatty acid, or fatty acyl-CoA alone
Registry number: EC 2.3.1.-
Synonym: actt-acyltransferase
(26 Jun 1999)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 1 ÆäÀÌÁö: 1
  • Lecithin Acyltransferase Deficiency - »õâ An autosomal recessively inherited disorder caused by mutation of LECITHIN CHOLESTEROL ACYLTRANSFERASE that facilitates the esterification of lipoprotein cholesterol and subsequent removal from peripheral tissues to the liver. This defect results in low HDL-cholesterol level in blood and accumulation of free cholesterol in tissue leading to a triad of CORNEAL OPACITY, hemolytic anemia (ANEMIA, HEMOLYTIC), and PROTEINURIA.
    Synonyms : Deficiency, Lecithin Acyltransferase, Dyslipoproteinemic Corneal Dystrophy, Fish-Eye Disease, LCAT Deficiency, Lecithin:Cholesterol Acyltransferase Deficiency, alpha-LCAT Deficiency, alpha-Lecithin-Cholesterol Acyltransferase Deficiency, Fish Eye Disease
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