| lactic acid oxidative decarboxylase | A flavoprotein oxidoreductase catalyzing oxidation (with O2) of l-lactate to acetate plus CO2 and water. Synonym: lactic acid oxidative decarboxylase. (05 Mar 2000) |
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| lactic acid | A byproduct of carbohydrate metabolism (anaerobic metabolism). A lactic acid level may be measured in the bloodstream in conditions of metabolic acidosis. Lactic acid is an intermediate product of carbohydrate metabolism and is derived mainly from muscle cells and red blood cells. Exercise will normally raise lactic acid levels. Conditions of oxygen deprivation (for example shock, heart failure, lung disease) will trigger anaerobic metabolism within muscle tissue resulting in lactic acid build up in the tissues. Normal lactic acid levels are 4.5 to 19.8 mg/dl. (25 Jun 1999) |
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| lactic acid bacillus | A member of the genus Lactobacillus. (05 Mar 2000) |
| lactic acid bacteria | <microbiology> A group of Gram-positive, non-sporing bacteria which carry out a lactic acid fermentation of sugars. It includes species of Lactobacillus, Leuconostoc, Pediococcus and Streptococcus. See: lactic acid fermentation. (25 Jun 1999) |
| lactic acid dehydrogenase | <enzyme> An enzyme with 5 forms: LDH-1 is in the heart, its blood level can rise when heart muscle is damaged. Other forms can be found in the liver, brain, kidney, skeletal muscle and bone. A useful blood test in the evaluation of many disease processes, including heart attack, liver disease, muscular dystrophy and bone disease. (27 Sep 1997) |
| lactic acid fermentation | <biochemistry> A type of fermentation carried out by lactic acid bacteria in which sugar (for example lactose, glucose, pentose) are converted either entirely (or almost entirely) to lactic acid (homolactic fermentation) or to a mixture of lactic acid and other products (heterolactic fermentation). (09 Oct 1997) |
| lactic acid level | <investigation> A test that measures the amount of lactic acid in the blood. (25 Jun 1999) |
| magnesium protoporphyrin monomethyl ester oxidative cyclase | <enzyme> In chlorophyll biosynthesis converts -(ch2)2-coo-ch3 side chain of mg protoporphyrin monomethyl ester to -c=o-ch-cooch3 ring of mg 2,4-divinyl phaeoporphyrin a(5) monomethyl ester; requires NADPH and molecular oxygen; similar to cytochrome p-450 catalyzed systems but not inhibited by co Registry number: EC 1.14.13.- Synonym: mpme-oxidative cyclase (26 Jun 1999) |
| mitochondrial oxidative damage endonuclease | <enzyme> An 8-oxog-specific DNA endonuclease from rat liver mitochondria; recognises and incises at 8-oxog and abasic acid sites in duplex DNA Registry number: EC 3.1.25.- Synonym: oxidative damage-specific endonuclease, mtode enzyme (26 Jun 1999) |
| oxidative | Having the power to oxidise; denoting a process involving oxidation. (05 Mar 2000) |
| oxidative metabolism | Respiration in the biochemical sense. (18 Nov 1997) |
| oxidative phosphorylation | <biochemistry> The phosphorylation of ATP coupled to the respiratory chain. (18 Nov 1997) |
| oxidative stress | A highly oxidized environment within cells that is thought to promote HIV replication because cells are forced into a highly activated state due to loss of control of their regulatory systems. (09 Oct 1997) |
| aromatic d-amino-acid decarboxylase | <enzyme> An enzyme that catalyses the decarboxylation of l-dopa to dopamine, of l-tryptophan to tryptamine, and of l-hydroxytryptophan to serotonin; important in the biosynthetic pathway of catecholamines and melanin. Synonym: dopa decarboxylase, hydroxytryptophan decarboxylase, tryptophan decarboxylase. (05 Mar 2000) |
| phenylacrylic acid decarboxylase | <enzyme> Confers resistance to phenylacrylic acids in yeasts; enzyme from bacillus pumilus catalyses nonoxidative conversion of ferulic acid and p-coumaric acid to 4-vinylguaiacol and 4-vinylphenol, respectively; amino acid sequence in first source Registry number: EC 4.1.1.- Synonym: cinnamic acid decarboxylase, ferulate decarboxylase, pad1 gene product, ferulic acid decarboxylase, 4-coumarate decarboylase, p-coumarate decarboxylase (26 Jun 1999) |
| orotidylic acid decarboxylase | <enzyme> An enzyme that catalyses the conversion of OMP to UMP and CO2; a defect or inhibition of this enzyme will result in orotic aciduria and orotidinuria; this enzyme is a part of pyrimidine biosynthesis. Compare: uridylic acid synthase. Synonym: OMP decarboxylase. (05 Mar 2000) |