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lactic a. a metabolic acidosis occurring as a result of excess lactic acid in the blood, due to conditions causing impaired cellular respiration. It occurs most commonly in disorders in which O2 is inadequately delivered to tissues, e.g., shock, septicemia, or extreme hypoxemia, but it can also result from exogenous or endogenous metabolic defects. Initially manifesting as hyperventilation, it progresses to mental confusion and coma.
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