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radio label A mildly radioactive molecule that is used to tag another molecule (such as a protein) so that it can be identified as it goes through some kind of biochemical process.
(09 Oct 1997)
chromogenic label A molecule which can be used as a label to a biological probe molecule because it forms a coloured compound when the probe molecule is attached to its target.
(09 Oct 1997)
off-label Use of a drug for a disease or condition other than the indication for which it was approved by the FDA. For example: many doctors prescribe paromomycin (humatin) for cryptosporidiosis, although it is not approved for treating this disease.
(09 Oct 1997)
off-label use In the United States, the regulations of the Food and drug administration (FDA) permit physicians to prescribe approved medications for other than their intended indications. This practice is known as off-label use.
(12 Dec 1998)
open-label trial A study in which both researchers and participants know what drug a person is taking and at what dose.
(09 Oct 1997)
label 1. To incorporate into a compound a substance that is readily detected, such as a radionuclide, whereby its metabolism can be followed or its physical distribution detected.
2. The substance so incorporated.
(05 Mar 2000)
fluorescent label A molecule which fluoresces and can be attached to a probe molecule that does not fluoresce.
(09 Oct 1997)
Abbott's method A method of treatment of scoliosis by use of a series of plaster jackets applied after partial correction of the curvature by external force.
(05 Mar 2000)
Abell-Kendall method A standard method for estimation of total serum cholesterol involving saponification of cholesterol ester by hydroxide, extraction with petroleum ether, and colour development with acetic anhydride-sulfuric acid; the method avoids interference by bilirubin, protein, and haemoglobin.
(05 Mar 2000)
activated sludge method A method of sewage disposal in which the sewage is treated with 15% bacterially active, liquid sludge, which is produced by repeated vigorous aeration of fresh sewage to form floccules or sediment; when this flocculation process is complete, the resulting activated sludge contains large numbers of bacteria, together with yeasts, molds, and protozoa, which actively effect the oxidation of organic compounds; this mixture is piped to a sedimentation tank, the effluent from which is completely treated sewage.
(05 Mar 2000)
Altmann-Gersh method The method of rapidly freezing a tissue and dehydrating it in a vacuum.
(05 Mar 2000)
Anel's method Ligation of an artery immediately above (on the proximal side of) an aneurysm.
(05 Mar 2000)
Antyllus' method Ligation of the artery above and below an aneurysm, followed by incision into and emptying of the sac.
(05 Mar 2000)
aristotelian method A method of study that stresses the relation between a general category and a particular object.
(05 Mar 2000)
Ashby method A differential agglutination method for estimating erythrocyte life span; compatible blood possessing a group factor that the recipient lacks is transferred to the recipient; after the transfusion, sera with potent agglutinins for the recipient's red cells are added to samples of the recipient's blood, and the unagglutinated red cells are counted; using this technique the red cell life span in normal persons is found to be 110 to 120 days.
(05 Mar 2000)
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