| tumor | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
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| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| Krukenberg, Adolph | <person> German anatomist, 1816-1877. See: Krukenberg's veins. (05 Mar 2000) |
| Krukenberg, Friedrich | <person> German pathologist, 1871-1946. See: Krukenberg's amputation, Krukenberg's spindle, Krukenberg's tumour. (05 Mar 2000) |
| Krukenberg's amputation | A cineplastic amputation at the carpus with the distal end of the forearm used to create a fork-like stump; especially valuable in the blind because the stump has proprioception. (05 Mar 2000) |
| Krukenberg's spindle | A vertical fusiform area of melanin pigmentation on the posterior surface of the central cornea. (05 Mar 2000) |
| Krukenberg's tumour | A metastatic carcinoma of the ovary, usually bilateral and secondary to a mucous carcinoma of the stomach, which contains signet-ring cells filled with mucus. (05 Mar 2000) |
| Krukenberg's veins | The terminal branches of the hepatic veins that lie centrally in the hepatic lobules and receive blood from the liver sinusoids. Synonym: venae centrales hepatis, Krukenberg's veins. (05 Mar 2000) |
| krukenberg tumour | <radiology> Ovarian metastasis of stomach carcinoma, also: colon, breast, other mucin-gland organs, 6% of malignant ovarian tumours (12 Dec 1998) |