| gtt | guttae; drops; ¹æ¿ï ¹æ¿ï |
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| KO | E-knockout |
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| GKO | IFN-gamma knockout |
| mice, knockout | Mice whose genome contains a gene whose function has been disrupted, or "knocked-out". A common method of producing disabled genes using recombinant DNA technology is by inserting an antibiotic resistance gene into the normal DNA sequence of a clone of the gene being studied. This disrupts the gene's action, thereby preventing it from making an active protein product. Cells in which this transfer is successful are then injected into mouse embryos, producing chimeric mice. These mice are bred to yield a strain in which all the cells contain the knocked-out gene. Knockout mice are used as animal models for various diseases, such as cystic fibrosis, and are helping to clarify the functions of the genes studied within the fields of immunology, cancer genetics, and developmental biology. (12 Dec 1998) |
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| knockout | <genetics, molecular biology> Informal term for the generation of a mutant organism in which the function of a particular gene has been completely eliminated (a null allele). See: homologous recombination, transposon. (18 Nov 1997) |
| antibiotic eye drops | <pharmacology> A medication that is pH balanced to allow placement into the eye for the purpose of killing bacteria. Examples include: Bleph-10, Chloromycetin, Cortisporin-Ophthalmic, Gantrisin, Genoptic, Gentacidin, Garamycin, Gantrisin, Ilotycin, Sodium Sulamyd and Sulphair. (27 Sep 1997) |
| burning drops sign | <clinical sign> In certain cases of perforated gastric ulcer, a sensation as of drops of hot liquid falling into the abdominal cavity or as of a stream of intensely hot liquid being poured into the cavity. (05 Mar 2000) |
| stomach drops | A stomachic tonic, usually tincture of gentian, alone or with other stomachics. (05 Mar 2000) |
| nose drops | A liquid preparation intended for intranasal administration with a medicine dropper. Most frequently used for decongestion of the nasal passages but can be used for any other appropriate indication. (05 Mar 2000) |
| drops | A popular term for a medicine taken in doses measured by drops's, usually a tincture, or applied by dropping, as an eyewash. (05 Mar 2000) |
| eye drops | See: eyewash, ophthalmic solutions. (05 Mar 2000) |
| knock-out drops | A popular name for chloral alcoholate given with criminal intent to produce unconsciousness rapidly; it is formed by adding chloral hydrate to beer or some stronger alcoholic liquor. (05 Mar 2000) |
| knockout drops | chloral hydrate in combination with alcohol |
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