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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 4 ÆäÀÌÁö: 1
  • Kininogen, High-Molecular-Weight - »õâ A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)
    Synonyms : Fitzgerald Factor, HMWK, High Molecular Weight Kininogen, High Molecular Weight Kininogens, High-Molecular-Weight Kininogens, Kininogens, High Molecular Weight, Kininogen, High Molecular Weight, Kininogens, High-Molecular-Weight
  • Kininogen, Low-Molecular-Weight - »õâ A protein, molecular weight 50 kD, located in various normal tissues. Upon cleavage by KALLIKREINS, it forms KALLIDIN. Kallidin, in turn, is converted into BRADYKININ. (From Stedman, 25th ed)
    Synonyms : LMWK, Low Molecular Weight Kininogen, Low Molecular Weight Kininogens, Low-Molecular-Weight Kininogens, Kininogen, Low Molecular Weight, Kininogens, Low-Molecular-Weight
  • Kininogens - »õâ Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
    Synonyms : Kininogen, Prekinins, Prokinins, T-Kininogen, Thiostatin, Kininogen Cystatins, T Kininogen
  • Kinins - »õâ A generic term used to describe a group of polypeptides with related chemical structures and pharmacological properties that are widely distributed in nature. These peptides are AUTACOIDS that act locally to produce pain, vasodilatation, increased vascular permeability, and the synthesis of prostaglandins. Thus, they comprise a subset of the large number of mediators that contribute to the inflammatory response. (From Goodman and Gilman's The Pharmacologic Basis of Therapeutics, 8th ed, p588)
    Synonyms :
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 1
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