| anemia | <haematology> Too few red blood cells in the bloodstream, resulting in insufficient oxygen to tissues and organs. Origin: Gr. Haima = blood (16 Dec 1997) |
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| algid pernicious fever | A pernicious malarial attack in which the patient presents symptoms of collapse and shock. (05 Mar 2000) |
| anaemia, pernicious | A megaloblastic anaemia occurring in children but more commonly in later life, characterised by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin b 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (12 Dec 1998) |
| pernicious | Tending to a fatal issue. Origin: L. Perniciosus (18 Nov 1997) |
| pernicious anaemia | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
| pernicious anaemia type rubriblast | The earliest of four maturation stages of the megaloblast. See: erythroblast. Synonym: pernicious anaemia type rubriblast. (05 Mar 2000) |
| pernicious malaria | <infectious disease> A tropical parasitic disease caused by one of the genus Plasmodium and carried by infected mosquitoes of the genus Anopheles. This parasite uses red blood cells to complete its reproductive cycle. Common symptoms of an attack include high fever, chills, sweats and body aches. (27 Sep 1997) |
| pernicious vomiting | Uncontrollable vomiting. (05 Mar 2000) |
| arthritis, juvenile rheumatoid | Rheumatoid arthritis of children occurring in three major subtypes defined by the symptoms present during the first six months following onset: systemic-onset (still's disease, juvenile-onset) polyarticular-onset, and pauciarticular-onset. Adult-onset cases of still's disease (still's disease, adult-onset) are also known. Only one subtype of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent. (12 Dec 1998) |
| benign juvenile melanoma | A benign, slightly pigmented or red superficial small skin tumour composed of spindle-shaped, epithelioid, and multinucleated cells that may appear atypical; most common in children, but also appearing in adults. Synonym: benign juvenile melanoma, epithelioid cell nevus, spindle cell nevus. (05 Mar 2000) |
| rheumatoid arthritis, systemic-onset juvenile | Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does appear and may persist after the systemic symptoms are gone. (12 Dec 1998) |
| periodontitis, juvenile | Localised periodontitis in teenagers and young adults. The onset is during the circumpubertal period but the diagnosis can be made beyond puberty. Lesions are confined predominantly to the first permanent molars or incisors and the distribution of lesions is usually symmetrical. The gingiva may appear normal. The lesions are highly active immediately following puberty but later destruction may slow or cease spontaneously. The disease is four times more prevalent in females than males and more prevalent in african americans than in other races or ethnic groups. (12 Dec 1998) |
| xanthogranuloma, juvenile | Benign disorder of infants and children characterised by multiple nodules with lipid-laden, non-langerhans-cell histiocytes. (12 Dec 1998) |
| systemic-onset juvenile chronic arthritis | See: Systemic-onset juvenile rheumatoid arthritis (still's disease). (12 Dec 1998) |
| systemic-onset juvenile rheumatoid arthritis | <rheumatology> A form of joint disease, arthritis, that presents with systemic upset. Clinical signs: high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis itself may not be immediately apparent but once apparent, it may persist after the systemic symptoms have resolved. Synonym: Still's disease. (03 Jul 1999) |