| isocitrate dehydrogenase |
Isocitrate dehydrogenase, also known as IDH, is an enzyme which participates in the citric acid cycle. It catalyzes the third step of the cycle: the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2 while converting NAD+ to NADH. ...
출처: en.wikipedia.org/wiki/Isocitrate_dehydrogenase
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| isocitrate dehydrogenase 1 |
[EC 1.1.1.41] a mitochondrial enzyme that catalyzes the oxidative decarboxylation of isocitrate to form α-ketoglutarate, using NAD+ as an electron acceptor; the reaction is the key rate-limiting step of the tricarboxylic acid cycle. The enzyme requires Mg2+ or Mn2+ and is activated by ADP, citrate, and Ca2+ and inhibited by NADH, NADPH, and ATP.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| isocitrate dehydrogenase 2 |
[EC 1.1.1.42] an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of isocitrate to form α-ketoglutarate, using NADP+ as an electron acceptor. The enzyme exists as two isozymes, one cytoplasmic and one mitochondrial, requires Mg2+ or Mn2+, and occurs in all tissues. The reaction serves to maintain the level of reducing equivalents within the cell.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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