| isochromosome | An abnormal chromosome with two identical arms due to duplication of one arm and loss of the other arm. (found in some girls with turner syndrome and in tumours.) (12 Dec 1998) |
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| isochromosomes | Metacentric chromosomes produced during meiosis or mitosis when the centromere splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion. (12 Dec 1998) |