| islet amyloid peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
|---|---|
| basic polypeptide-activated protein kinase | <enzyme> Requires mn2+ for its activity; from bombyx mori; does not require cyclicamp, cyclicgmp or ca Registry number: EC 2.7.1.- Synonym: ba kinase (26 Jun 1999) |
| vasoactive intestinal polypeptide | A polypeptide hormone secreted most commonly by non-beta islet cell tumours of the pancreas, producing copious watery diarrhoea and faecal electrolyte loss, particularly hypokalaemia; VIP increases the rates of glycogenolysis; stimulates pancreatic bicarbonate secretion. Synonym: vasoactive intestinal peptide. (05 Mar 2000) |
| pancreatic polypeptide | <chemical> A 36-amino acid polypeptide with physiological regulatory functions. It is secreted by pancreatic tissue. Plasma pancreatic polypeptide increases after ingestion of food, with age, and in disease states. A lack of pancreatic polypeptide in the islets of langerhans has been associated with the obese syndrome in rats and mice. Chemical name: Pancreatic polypeptide (12 Dec 1998) |
| gastric inhibitory polypeptide | <hormone> Peptide hormone (43 amino acids) that stimulates insulin release and inhibits the release of gastric acid and pepsin. Acronym: GIP (18 Nov 1997) |
| photosystem II D1 polypeptide carboxy-terminal processing protease | <enzyme> From thylakoids; not inhibited by common protease inhibitors Registry number: EC 3.4.99.- Synonym: d1 carboxy-terminal processing protease, d1 c-terminal protease, ctpa gene product (26 Jun 1999) |
| polypeptide | <biochemistry> A peptide which on hydrolysis yields more than two amino acids, called tripeptides, tetrapeptides, etc. According to the number of amino acids contained. (14 Oct 1997) |
| polypeptide fucosyltransferase | <enzyme> From cho cells; attaches fucose through an o-glycosidic linkage to serine or theonine in egf domains Registry number: EC 2.4.1.- Synonym: GDPfucose - polypeptide fucosyltransferase (26 Jun 1999) |
| polypeptide N-acetylgalactosominyltransferase | <enzyme> N-acetylgalactosaminyl residue is transferred to threonine or serine hydroxyl groups Registry number: EC 2.4.1.41 Synonym: protein-udpacetylgalactosaminyltransferase, udp-n-acetylgalactosamine mucin transferase, udp-n-acetylgalactosamine-polypeptide n-acetylgalactosamine transferase, udpacetylgalactosamine-protein acetylgalactosaminyltransferase, udp-gpagat, udp-galnac-polypeptide, n-acetylgalactosaminyltransferase, galnac-transferase, udp-galnac-polypeptide n-acetylgalactosaminyltransferase (26 Jun 1999) |
| tissue polypeptide antigen | Serological tumour marker composed of a molecular complex of cytokeratins 8, 18, and 19. It is used in the diagnosis and staging of bronchogenic carcinoma. (12 Dec 1998) |
| trefoil polypeptide | A group of polypeptides that share the trefoil moiety of a highly stable three-loop structure held together by disulfide bonds based on cysteine residues; they are widely expressed in gastrointestinal tissues and secreted by mucous cells; their functions are as yet unknown. (05 Mar 2000) |
| adenoma, islet cell | A benign tumour of the islets of langerhans that may occur anywhere throughout the pancreas. Such tumours may result in hyperinsulinism or zollinger-ellison syndrome. (12 Dec 1998) |
| blood islet | An aggregation of splanchnic mesodermal cells on the embryonic yolk sac, with the potentiality of forming vascular endothelium and primitive blood cells. Synonym: blood islet. (05 Mar 2000) |
| carcinoma, islet cell | A carcinoma of the islets of langerhans. (12 Dec 1998) |
| pancreatic isleT-cell tumours | <radiology> Insulinoma (beta-cell), usually solitary, 85% benign, gastrinoma, small, slow-growing, multiple, 60% malignant, Zollinger-Ellison syndrome: mult. Intractable ulcers, VIPoma, vasoactive intestinal peptide (VIP), WDHA syndrome: watery diarrhoea, hypokalaemia, achlorhydria, Verner-Morrison syndrome, glucagonoma, hyperglycaemia, migratory necrolytic erythema APUDomas, associated with MEN-1 (12 Dec 1998) |