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antimony sodium gluconate <chemical> Antimony complex where the metal may exist in either the pentavalent or trivalent states. The pentavalent gluconate is used in leishmaniasis. The trivalent gluconate is most frequently used in schistosomiasis.
Pharmacological action: antiprotozoal agents, schistosomicides.
(12 Dec 1998)
calcium gluconate <chemical> D-gluconic acid calcium salt (2:1). The calcium salt of gluconic acid. The compound has a variety of uses, including its use as a calcium replenisher in hypocalcaemic states.
Chemical name: D-Gluconic acid, calcium salt (2:1)
(12 Dec 1998)
gluconate 5-dehydrogenase <enzyme> Catalyses conversion of gluconic acid to 5-ketogluconic acid; genbank x80019(gno)
Registry number: EC 1.1.1.69
Synonym: gluconate-nadp 5-oxidoreductase, gno dehydrogenase, gno gene product
(26 Jun 1999)
gluconate permease <chemical> Gntp(bs) isolated from bacillus subtilis
Chemical name: permease, gluconate
Synonym: gntp gene product, gntp(bs) gene product
(26 Jun 1999)
phospho-2-keto-3-deoxy-gluconate aldolase <enzyme> Minor descriptor (75-84); on-line and index medicus search aldehyde-lyases (75-84)
Registry number: EC 4.1.2.14
Synonym: 2-keto-3-deoxy-6-phosphogluconate aldolase, 6-phospho-2-keto-3-deoxy-d-gluconate d-glyceraldehyde-3-phosphate-lyase, kdpga
(26 Jun 1999)
potassium gluconate Gluconic acid potassium salt, used in hypokalaemia as a replenisher.
(05 Mar 2000)
ferrous gluconate Iron gluconate; a haematinic.
(05 Mar 2000)
2,5-diketo-D-gluconate 5-reductase <enzyme> Catalyses reversibly the stereospecific NADPH-dependent reduction of 2,5-diketo-d-gluconate to 2-keto-l-gluconate
Registry number: EC 1.1.1.-
Synonym: 2,5-dkg reductase
(26 Jun 1999)
albuminised iron Iron albuminate, a compound of iron oxide and albumin; rendered soluble by the presence of sodium citrate; occurs as reddish brown, lustrous granules, odourless or nearly so; used in anaemia.
(05 Mar 2000)
anaemia, iron deficiency Deficiency of iron results in anaemia because iron is necessary to make haemoglobin, the key molecule in red blood cells responsible for the transport of oxygen. In iron deficiency anaemia, the red cells are unusally small (microcytic) and pale (hypochromic). Characteristic features of iron deficiency anaemia in children include failure to thrive (grow) and increased infections. The treatment of iron deficiency anaemia, whether it be in children or adults, is with iron and iron-containing foods. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men.
Anaemia characterised by low or absent iron stores, low serum iron concentration, elevated free erythrocyte porphorin, low transferrin saturation, elevated transferrin, low serum ferritin, low haemoglobin concentration or haematocrit, and hypochromic microcytic red blood cells. Symptoms may include pallor, angular stomatitis and other oral lesions, gastrointestinal complaints, retinal haemorrhages and exudates, and thinning and brittleness of the nails. Among the causes of iron-deficiency anaemia are inadequate iron intake, impaired iron absorption, increased blood loss and increased requirements such as infancy, pregnancy, and lactation.
(12 Dec 1998)
brain iron <radiology> Normal, Infant: NONE, Adult: globus pallidum, substantia nigra, red nucleus, dentate nucleus, Aging: (adult) and putamen, Degenerative disease, Parkinson disease: putamen, SN compacta, Huntington disease: caudate, putamen, Alzheimer disease: cerebral cortex, Hallervorden-Spatz disease, MS: thalamus, putamen, Others, AVM: malformation and rim, Bleed: rim macrophages, Haemorrhagic CVA: gyral / basal ganglia MRI: low T1 and T2 signal
(12 Dec 1998)
peptonised iron A compound of iron oxide and peptone, rendered soluble by the presence of sodium citrate; used in the treatment of iron deficiency anaemia.
(05 Mar 2000)
molybdenum-iron protein aldehyde oxidoreductase <enzyme> Related to xanthine oxidase; isolated from desulfovibrio gigas
Registry number: EC 1.2.7.-
Synonym: mop protein
(26 Jun 1999)
Weigert's iron haematoxylin stain <technique> A nuclear staining solution containing haematoxylin, ferric chloride, and hydrochloric acid; useful in combination with von Gieson's stain, especially for demonstrating connective tissue elements or Entamoeba histolytica in sections.
(05 Mar 2000)
Mowry's colloidal iron stain <technique> A stain used for demonstrating acid mucopolysaccharides.
(05 Mar 2000)
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