| interleukin-1 | <cytokine> A soluble protein (17 kD: 152 amino acids) secreted by monocytes, macrophages or accessory cells involved in the activation of both T-lymphocytes and B lymphocytes and potentiates their response to antigens or mitogens. Its biological effects include the ability to replace macrophage requirements for T-cell activation, as well as affecting a wide range of other cell types. at least two IL-1 genes are active and alpha and beta forms of IL-1 are recognised. It is released early in an immune system response by monocytes and macrophages. It stimulates T-cell proliferation and protein synthesis. Another effect of IL-1 is that it causes fever. See: catabolin, endogenous pyrogen. Acronym: IL-1 (12 Dec 1998) |
|---|---|
| interleukin-1 converting enzyme | <biochemistry> Cytoplasmic cysteine protease that is uniquely responsible for cleaving proIL-1_ (31 or 33 kD) into mature IL-1_ (17.5 kD), the active cytokine is then released by a nonstandard mechanism (there is no signal sequence and it does not pass through the Golgi). The enzyme seems to be composed of two nonidentical subunits derived from a single proenzyme. The ICE gene has some homology with the ced 9 gene of C. Elegans, the product of which is involved in mediating cell death by apoptosis. (11 Mar 1998) |
| interleukin-10 | <cytokine> A factor produced by Th2 helper T-cells, some B-cells and LPS activated monocytes. It is a coregulator of mast cell growth. It is produced by T-cells and B-cells and shows extensive homology with the Epstein-Barr virus bcrfi gene. Chemical name: Cytokine formation-inhibiting factor (mouse clone F115 protein moiety reduced) Acronym: IL-10 (12 Dec 1998) |
| interleukin-11 | <cytokine> Pleiotropic cytokine originally isolated from primate bone marrow stromal cell line that has the ability to modulate antigen-specific antibody responses, potentiate megakaryocytes, and regulate bone marrow adipogenesis. Stimulates T-cell dependent B-cell maturation, megakaryopoiesis, various stages of myeloid differentiation. Receptor probably a tyrosine kinase. Acronym: IL-11 (12 Dec 1998) |
| interleukin-12 | <cytokine> A 75 kD heterodimeric cytokine composed of disulfide-bonded 40 kD and 35 kD subunits that was originally identified by its ability to induce cytotoxic effector cells in synergy with less than optimal concentrations of interleukin-2. It is released by macrophages in response to infection and promotes the activation of cell-mediated immunity. Specifically, IL-12 triggers the maturation of Thl CD4 cells, specific cytotoxic T-lymphocyte responses and an increase in the activity of NK cells and consequently, it is the initiator of cell-mediated immunity. It enhances the lytic activity of NK cells, induces interferon production, stimulates the proliferation of activated T-cells and NK cells. Is secreted by human B lymphoblastoid cells (NC 37). May play a role in controlling immunoglobulin isotype selection as it also inhibits IgE synthesis (even in the presence of anti-IFN monoclonal antibody) and as a growth factor for activated CD4+ and CD8+ T-cells independently of interleukin-2, and for CD56+ NK cells but not resting peripheral blood mononuclear cells or resting or activated tonsillar B-cells. It is likely that interleukin 12 has a major role in protective immunity against viruses and is under study as an immunotherapy in HIV infection. Formerly referred to as cytotoxic lymphocyte maturation factor. Acronym: IL-12 (12 Dec 1998) |
| interleukin-13 | <cytokine> A T-lymphocyte-derived cytokine that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-lymphocytes. It appears to play a role in regulating inflammatory and immune responses and has anti-inflammatory activity. Produced by activated T-cells, inhibits IL-6 production by monocytes and also the production of other pro inflammatory cytokines such as TNF, IL-1, IL-8. Stimulates B-cells. Gene is located in cluster of genes on human chromosome 5q that also has IL-4 gene. Acronym: IL-13 (12 Dec 1998) |
| interleukin-14 | Cytokine that induces B-cell proliferation, inhibits immunoglobulin secretion, and selectively expands certain B-cell subpopulations. Acronym: IL-14 (12 Dec 1998) |
| interleukin-15 | Cytokine that stimulates the proliferation of T-lymphocytes and shares biological activities with il-2. Il-15 also can induce b-lymphocyte proliferation and differentiation. Acronym: IL-15 (12 Dec 1998) |
| interleukin-16 | Cytokine produced by activated T-lymphocytes that stimulates the migration of CD4-positive lymphocytes and monocytes. It has been reported to suppress HIV replication. (12 Dec 1998) |
Synonyms : Epidermal Cell Derived Thymocyte-Activating Factor, Interleukin I, Macrophage Cell Factor, T Helper Factor, Epidermal Cell Derived Thymocyte Activating Factor, Interleukin 1, Lymphocyte Activating Factor
Synonyms : IL-1RAcP, Interleukin 1 Receptor Accessory Protein
Synonyms : IL-1 Receptor-Associated Kinase, IRAK Kinases, IRAK-1 Kinase, IRAK-2 Kinase, IRAK-3 Kinase, IRAK-4 Kinase, Interleukin-1 Receptor-Associated Kinase, Interleukin-1 Receptor-Associated Kinase 1, Interleukin-1 Receptor-Associated Kinase 2, IRAK 1 Kinase
Synonyms : CSIF-10, Cytokine Synthesis Inhibitory Factor, IL10, Interleukin 10
Synonyms : IL-10R1 Receptor, Interleukin-10 Receptor 1, IL 10R1 Receptor, Interleukin 10 Receptor 1, Interleukin 10 Receptor alpha Chain, Interleukin 10 Receptor alpha Subunit, Receptor, IL-10R1
| interleukin-1 |
Interleukin-1 (IL-1) is secreted by the macrophages, monocytes and dendritic cells. It is an important part of the inflammatory response. It increases the expression of adhesion factors on endothelial cells to enable transmigration of leukocytes. It also re-sets the hypothalamus thermoregulatory center, leading to an increased body temperature which expresses itself as fever. It is therefore called an endogenous pyrogen. ...
출처: en.wikipedia.org/wiki/Interleukin-1
|
|---|---|
| interleukin-1 |
IL-1. A type of biological response modifier that stimulates immune system cells that fight disease, and is involved in inflammatory responses. There are two forms of IL-1, IL-1 alfa and IL-1 beta. Both forms of IL-1 are produced by the body, and can also be made in the laboratory.
출처: www.stjude.org/glossary
|
| interleukin-1 |
Signalling molecule involved in the inflammatory response that can act as an endogenous pyrogen.
출처: www.nature.com/nrn/journal/v2/n3/glossary/nrn0301_...
|
| interleukin-11 |
A substance that stimulates immune response and may reduce toxicity to the gastrointestinal system resulting from cancer therapy. Also called IL- I 1.
출처: nydailynews.healthology.com/nydailynews/15836.htm
|
| interleukin-12 |
A substance that enhances the ability of the immune system to kill tumor cells, and that may interfere with blood flow to the tumor. Also called IL- 1 2.
출처: nydailynews.healthology.com/nydailynews/15836.htm
|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|