| nephrogenic diabetes insipidus | Diabetes insipidus due to inability of the kidney tubules to respond to antidiuretic hormone; X-linked inheritance, with full expression in males and partial defect in heterozygous females. Synonym: vasopressin-resistant diabetes. (05 Mar 2000) |
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| diabetes insipidus | <disease, endocrinology> Rare form of diabetes in which the kidney tubules do not reabsorb sufficient water. This can be because (a) either the renal tubules have defective receptors for antidiuretic hormone (ADH, vasopressin) or (b) a class of aquaporin water channel in the collecting duct is defective or (c) there is inadequate ADH production by the pituitary, leading to the excessive production of dilute urine. (18 Nov 1997) |
| diabetes insipidus, nephrogenic | A rare congenital and familial form of diabetes insipidus, resulting from failure of the renal tubules to absorb water. There is excessive production of antidiuretic hormones but the tubules fail to respond to it. (12 Dec 1998) |