| insert | 1. An additional length of base pairs in DNA that has been introduced into that DNA. 2. An additional length of bases that has been introduced into RNA. 3. An additional length of amino acids that has been introduced into a protein. (05 Mar 2000) |
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| inserted | Attached to, arising from. (09 Oct 1997) |
| insertin | <protein> Protein (30 kD) from chicken gizzard smooth muscle. Binds to the barbed ends of actin filaments and apparently allows insertion of further monomers. (18 Nov 1997) |
| insertion | 1. <anatomy> The place of attachment, as of a muscle to the bone which it moves. 2. <genetics> A rare nonreciprocal translocation involving three breaks in which a segment is removed from one chromosome and then inserted into a broken region of a nonhomologous chromosome. Origin: L. Inserere = to join to (18 Nov 1997) |
| insertion mutation | A mutation caused by the insertion of at least one extra nucleotide basein a DNA sequence. (09 Oct 1997) |
| insertion sequence | Mobile nucleotide sequences that occur naturally in the genomes of bacterial populations. When inserted into bacterial DNA, they inactivate the gene concerned, when they are removed the gene regains its activity. Closely related to transposons and range in size from a few hundred to a few thousand bases, but are usually less than 1500 bases. (18 Nov 1997) |
| insertional inactivation | The inactivation of a gene due to the insertion of exogenous genetic material into that gene. (14 Nov 1997) |
| insertional mutagenesis | Generally, mutagenesis of DNA by the insertion of one or more bases. Specific examples: 1. Oncogenesis by insertion of a retrovirus adjacent to a cellular proto-oncogene. 2. A strategy of mutagenesis with transposons. After a round of transposition, progeny are screened by PCR, with transposon and gene specific primers, for the proximity of the transposon sequence to the gene of interest. As PCR can only produce products up to 1-2 kb, a large fraction of progeny identified as positive by PCR will have a transposon close enough to the gene to inactivate or otherwise alter its pattern of expression. (18 Nov 1997) |
| insertosome | Mobile nucleotide sequences that occur naturally in the genomes of bacterial populations. When inserted into bacterial DNA, they inactivate the gene concerned, when they are removed the gene regains its activity. Closely related to transposons and range in size from a few hundred to a few thousand bases, but are usually less than 1500 bases. (18 Nov 1997) |
| package insert | <pharmacology> A form containing the indications, side effects and other relevant information known about a drug that can be found on the inside of any prescription drug container. (09 Oct 1997) |
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| metal insert teeth | Prosthetic teeth containing metal cutting surfaces in the occlusal surfaces. (05 Mar 2000) |