| inotropic a. |
any of a class of agents affecting the force of muscle contraction, particularly a drug affecting the force of cardiac contraction; positive inotropic agents, such as digitalis glycosides or catecholamines, increase and negative inotropic agents, such as calcium antagonists, decrease the force of cardiac muscle contractions. All such drugs currently used act indirectly, as by affecting sodium pump, calcium transport, or cyclic AMP production, rather than by directly affecting myofibrils or troponin complexes.
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