| inosine 5'-triphosphate | Inosine with triphosphoric acid esterified at its 5' position; participates in a number of enzyme-catalyzed reactions. Acronym: ITP (05 Mar 2000) |
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| inosine triphosphate | <chemical> Inosine 5'-(tetrahydrogen triphosphate). An inosine nucleotide containing three phosphate groups esterified to the sugar moiety. Synonym: irppp. Chemical name: Inosine 5'-(tetrahydrogen triphosphate) (12 Dec 1998) |
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| inosine | The fifth base of nucleic acids. Important because it fails to form specific pair bonds with the other bases. In transfer RNAs, this property is used in the anticodon to allow matching of a single tRNA to several codons. PCR perfomed with primers containing inosine tolerates a limited degree of mismatch between primer and template, useful in homology probing. (18 Nov 1997) |
| inosine 5'-diphosphate | Inosine esterified at its 5' position with diphosphoric acid. Acronym: IDP (05 Mar 2000) |
| inosine diphosphate | <chemical> Inosine 5'-(trihydrogen diphosphate). An inosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonym: irpp; inosine pyrophosphate. Chemical name: Inosine 5'-(trihydrogen diphosphate) (12 Dec 1998) |
| inosine monophosphate | <chemical> Inosine 5'-monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Chemical name: 5'-Inosinic acid (12 Dec 1998) |
| inosine pranobex | <chemical> An alkylamino-alcohol complex of inosine that may have some antiviral activity, probably due to its inhibition of viral protein synthesis and facilitation of the host's mRNA synthesis. Pharmacological action: adjuvants, immunologic, antiviral agents. Chemical name: Inosine, compd. With 1-(dimethylamino)-2-propanol 4-(acetylamino)benzoate (salt) (1:3) (12 Dec 1998) |
| inosine triphosphatase | <enzyme> Releases pyrophosphate + imp Registry number: EC 3.6.1.- Synonym: itpase, inosine triphosphate pyrophosphohydrolase, itp pyrophosphohydrolase (26 Jun 1999) |
| inosine-uridine hydrolase | <enzyme> From crithidia fasciculata; hydrolyzes the n-glycosidic bonds of purine and pyrimidine nucleosides Registry number: EC 3.2.2.- Synonym: inosine-uridine preferring nucleoside hydrolase, iu-nucleoside hydrolase (26 Jun 1999) |
| adenosine 5'-triphosphate | Adenosinepyrophosphate;adenosine with triphosphoric acid esterfied at its 5' position; immediate precursors of adenine nucleotides in RNA. The primary energy currency of a cell. Synonym: adenosine triphosphate. Acronym: ATP (05 Mar 2000) |
| adenosine triphosphate | <biochemistry> A nucleotide present in all living cells which serves as an energy source for many metabolic processes and is required for ribonucleic acid synthesis. (06 May 1997) |
| arabinofuranosylcytosine triphosphate | <chemical> A triphosphate nucleotide analog which is the biologically active form of cytarabine. It inhibits nuclear DNA synthesis. Pharmacological action: nucleic acid synthesis inhibitors. Chemical name: 2(1H)-Pyrimidinone, 4-amino-1-(5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-arabinofuranosyl)- (12 Dec 1998) |
| ribonucleoside-triphosphate reductase | <enzyme> Requires a cobamide coenzyme and ATP Registry number: EC 1.17.4.2 Synonym: rtp reductase (26 Jun 1999) |
| guanosine 5'-triphosphate | An immediate precursor of guanine nucleotides in RNA; similar to ATP; has a crucial role in microtubule formation. GTP cyclohydrolase, an enzyme that catalyses the reaction of GTP and H2O forming formate and a precursor of tetrahydrobiopterin; a deficiency of this enzyme will result in one form of malignant hyperphenylalaninaemia. Acronym: GTP (05 Mar 2000) |
| guanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase | <enzyme> Catalyses the hydrolysis of guanosine 5'-triphosphate, 3'-diphosphate to yield guanosine 5'-diphosphate, 3'-diphosphate and orthophosphate; from E coli; also hydrolyzes other guanosine 5'-triphosphate derivatives with at least one unsubstituted phosphate group on the 3'-position, but not GTP, ATP or adenosine 5'-triphosphate, 3'-diphosphate Registry number: EC 3.6.1.40 Synonym: guanosine pentaphosphate phosphohydrolase, GTPdp pyrophosphatase, pppgpp 5'-phosphohydrolase, guanosine 5'-triphosphate-3'diphosphate 5'-phosphohydrolase, pppgpp-5'-phosphohydrolase, pppgpp-5'-phosphatase (26 Jun 1999) |
| guanosine 5'-triphosphate 3'-diphosphate pyrophosphorylase | <enzyme> Yields pyrophosphate + pppg Registry number: EC 2.7.7.- Synonym: pppgpp pyrophosphorylase (26 Jun 1999) |