| IPSC | inhibitory postsynaptic current |
|---|---|
| IPSP | inhibitory postsynaptic potential |
| EPSC | excitatory postsynaptic current |
| EPSP | excitatory postsynaptic potential |
| PSD | particle size distribution; peptone, starch, and dextrose; periodic synchronous discharge; phase-sen... |
| mIPSC | Miniature inhibitory postsynaptic currents |
|---|---|
| sIPSCs | Spontaneous inhibitory postsynaptic currents |
| EPSC | Excitatory postsynaptic current |
| f-EPSPs | Fast excitatory postsynaptic potentials |
| fEPSP | Field excitatory postsynaptic potential |
| inhibitory postsynaptic potential | The change in potential produced in the membrane of the next neuron when an impulse which has an inhibitory influence arrives at the synapse; it is a local change in the direction of hyperpolarization; the frequency of discharge of a given neuron is determined by the extent to which impulses that lead to excitatory postsynaptic potential's predominate over those that cause inhibitory postsynaptic potential's. (05 Mar 2000) |
|---|---|
| postsynaptic | Pertaining to the area on the distal side of a synaptic cleft. (05 Mar 2000) |
| postsynaptic cell | In a chemical synapse, the cell that receives a signal (binds neurotransmitter) from the presynaptic cell and responds with depolarisation In an electrical synapse, the postsynaptic cell would just be downstream, but since many electrical synapses are rectifying, one of the two cells involved will always be postsynaptic. (18 Nov 1997) |
| postsynaptic membrane | That part of the plasma membrane of a neuron or muscle fibre with which an axon terminal forms a synaptic junction; in many instances, at least part of such a small postsynaptic membrane patch shows characteristic morphological modifications such as greater thickness and higher electron-density, believed to correspond to the transmitter-sensitive receptor site of such synapses. (05 Mar 2000) |
| postsynaptic potential | In a synapse, a change in the resting potential of a postsynaptic cell following stimulation of the presynaptic cell. For example: in a cholinergic synapse, the release of acetylcholine from the presynaptic cell causes channels to open in the postsynaptic cell. Each channel opening causes a small depolarisation, known as a miniature end plate potential (mepp), these sum to produce an excitatory postsynaptic potential. (18 Nov 1997) |
| excitatory postsynaptic potential | The change in potential which is produced in the membrane of the next neuron when an impulse which has an excitatory influence arrives at the synapse; it is a local change in the direction of depolarisation; summation of these potential's can lead to discharge of an impulse by the neuron. (05 Mar 2000) |
| excitatory postsynaptic potentials | The change in potential produced in the membrane of the next neuron when an impulse which has an excitatory influence arrives at the synapse; it is a local change in the direction of depolarisation; summation of these potentials can lead to discharge of an impulse by the neuron. (12 Dec 1998) |
| macrophage migration-inhibitory factors | Proteins released by sensitised lymphocytes and possibly other cells that inhibit the migration of macrophages away from the release site. The structure and chemical properties may vary with the species and type of releasing cell. (12 Dec 1998) |
| gastric inhibitory polypeptide | <hormone> Peptide hormone (43 amino acids) that stimulates insulin release and inhibits the release of gastric acid and pepsin. Acronym: GIP (18 Nov 1997) |
| G-protein, inhibitory GI | A g-protein that inhibits adenylyl cyclase and activates k+ channels. (12 Dec 1998) |
| migration-inhibitory factor | <growth factor> A soluble, nondialysable factor that is produced by sensitised lymphocytes following exposure to a specific antigen. It inhibits macrophage migration and causes adherence. It was originally defined on the basis of inhibition of emigration of mononuclear cells from capillary (haematocrit) tubes, more recently a 13 kD protein with migration inhibitory activity has been isolated. Acronym: MIF Synonym: inhibition factor. (22 Sep 2002) |
| migration-inhibitory factor test | A test which measures the presence of migration-inhibitory factor. Usually peritoneal macrophages are placed in a capillary tube in the presence or absence of supernatants from activated T-cells. If MIF is present, the migration of monocyte/macrophages is reduced. Synonym: macrophage migration inhibition test, migration inhibition test. (05 Mar 2000) |
| minimal inhibitory concentration | <microbiology, pharmacology> The lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro. (05 Mar 2000) |
| inhibitory | Of or pertaining to, or producing, inhibition; consisting in inhibition; tending or serving to inhibit; as, the inhibitory action of the pneumogastric on the respiratory center. "I would not have you consider these criticisms as inhibitory. <physiology> " (Lamb) Inhibitory nerves, those nerves which modify, inhibit, or suppress a motor or secretory act already in progress. Origin: LL. Inhibitorius: cf. F. Inhibitoire. Source: Websters Dictionary (01 Mar 1998) |
| inhibitory fibres | Nerve fibre's that inhibit the activity of the nerve cells with which they have synaptic connections, or of the effector tissue (smooth muscle, heart muscle, glands) in which they terminate. (05 Mar 2000) |
| inhibitory postsynaptic p. |
a transient hyperpolarization of membrane potential induced in a postsynaptic neuron when subjected to a volley of impulses over an inhibitory afferent pathway, resulting in a diminished responsiveness of the neuron. Abbreviated IPSP.
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