| 영문 | immunosuppressant | 한글 | 면역억제제 |
|---|---|---|---|
| 설명 | 면역억제에는 그 반응만을 억제하는 특이한 것과 그렇지 않은 것이 있으며, 이론적으로는 특이한 쪽의 작용이 뛰어나야 하겠지만, 임상적으로 쓰이는 것은 거의 비특이적 면역억제제이다. 비특이적 면역억제제에는 사이클로포스파미드-니트로겐머스타드 등의 알킬화제, 6-메르캅토푸린-아자티오푸린-시토신아라비노시드 등과 같은 대사대항제, 미토마이신 C-악티노마이신 D 등의 항생물질, 부신겉질스테로이드제-빈카알칼로이드제-항림프구혈청 등의 항체 등 여러 종류의 약제가 있다. 이들 면역억제제는 항원자극에서 항체생성까지 이르는 동안에, 큰포식세포에 의한 항원의 탐식, 림프구에 의한 항원인식, 세포분열, T세포와 B세포의 분열, 항체생성 등 몇 가지 과정을 저해시킴으로써 면역억제를 야기시킨다. 대부분이 항종양 활성을 가지고 있어서, DNA장애, DNA합성저지 등을 매개로 하여 세포분열을 저지한다. 부작용으로는 위장장애-탈모-간장애-무정자증, 악성종양 등의 발생률이 높기 때문에 이를 사용할 때는 충분히 경과를 관찰해야 한다. |
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| immunosuppressant | <immunology, pharmacology> An agent capable of suppressing immune responses. (18 Nov 1997) |
|---|---|
| immunosuppressed | <immunology> Condition of having a lowered resistance to disease. May be a temporary result of lowered white blood cells from chemotherapy administration. (09 Oct 1997) |
| immunosuppression | <immunology> This occurs when T and/or B clones of lymphocytes are depleted in size or suppressed in their reactivity, expansion or differentiation. It may arise from activation of specific or non-specific T suppressor lymphocytes of either T or B clones or by drugs that have generalised effects on most or all T or B lymphocytes. Cyclosporin A and FK506 act on T-cells, as does antilymphocyte serum, alkylating agents such as cyclophosphamide are less specific in their action and damage DNA replication, while base analogues interfering with guanine metabolism act in a similar way. See: immunophilin. (18 Nov 1997) |
| immunosuppressive | 1. Denoting or inducing immunosuppression. Synonym: immunosuppressant. (05 Mar 2000) |
| immunosuppressive agent | <immunology, pharmacology> Any chemotherapeutic agent which also has the effect of suppressing the immune system. most often these agents will reduce the absolute number of white blood cells in the bloodstream. (27 Sep 1997) |
| immunosuppressive agents | Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of suppressor T-cell populations or by inhibiting the activation of helper cells. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of interleukins and other cytokines are emerging. (12 Dec 1998) |
| immunosuppressive drugs | Drugs that block the bodys ability to fight infection or foreign substances that enter the body. A person receiving an organ transplant is given these drugs to stop the body from rejecting the new organ or tissue. Cyclosporin is a commonly used immunosuppressive drug. (09 Oct 1997) |
Synonyms : Anti-Rejection Therapy, Therapy, Anti-Rejection, Therapy, Antirejection, Anti Rejection Therapy, Anti-Rejection Therapies, Antirejection Therapies, Immunosuppressions
Synonyms : Immunosuppressants, Agents, Immunosuppressive
| immunosuppressant |
a drug that lowers the body's normal immune response
출처: wordnet.princeton.edu/perl/webwn
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|---|---|
| immunosuppression |
lowering the body's normal immune response to invasion by foreign substances; can be deliberate (as in lowering the immune response to prevent rejection of a transplanted organ) or incidental (as a side effect of radiotherapy or chemotherapy for cancer)
출처: wordnet.princeton.edu/perl/webwn
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| immunosuppressive |
immunosuppressant: a drug that lowers the body's normal immune response
출처: wordnet.princeton.edu/perl/webwn
|
| immunosuppression |
Suppression of the body's immune system and its ability to fight infections or disease. Immunosuppression may be deliberately induced with drugs, as in preparation for bone marrow or other organ transplantation to prevent rejection of the donor tissue. It may also result from certain diseases such as AIDS or lymphoma or from anticancer drugs.
출처: www.stjude.org/glossary
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| immunosuppressant |
a drug that inhibits the activity of the immune system; used to prevent rejection of a transplant organ and in disorders where the body's immune system attacks its own tissues
출처: www.american-depot.com/services/resources_gl_i.asp
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| immunosuppress | a drug that lowers the body's normal immune response |
|---|---|
| immunosuppress | of persons whose immune response is inadequate |
| immunosuppress | lowering the body's normal immune response to invasion by foreign substances |
| immunosuppress | of or relating to a substance that lowers the body's normal immune response |
| immunosuppress | a drug that lowers the body's normal immune response |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|