| immunological disease | <immunology> Any illness, such as an allergy, that is caused by the action of antibodies. (09 Oct 1997) |
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| models, immunological | Theoretical representations that simulate the behaviour or activity of immune system, processes, or phenomena. They include the use of mathematical equations, computers, and other electrical equipment. (12 Dec 1998) |
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| immunological | Pertaining to immunology. (18 Nov 1997) |
| immunological competence | <immunology> The bodys ability to develop an immune response to infection or disease. Immunocompetence is measured to see how well the body can fight off certain disease. Many cancer patients become immunocompromised, where their immune system is not as strong as a healthy person's. (16 Dec 1997) |
| immunological deficiency | Inabillity to mount a normal immune response. Immunodeficiency can be due to a genetic disease or acquired as in aids due to HIV. (12 Dec 1998) |
| immunological enhancement | In immunology, the potentiating effect of specific antibody in establishing and in delaying rejection of a tumour allograft; aside from antibody, non-specific substances may also act to enhance immune response. Synonym: immunological enhancement. (05 Mar 2000) |
| immunological mechanism | The groups of cells (chiefly lymphocytes and cells of the reticuloendothelial system) that function in establishing active acquired immunity (induced sensitivity, allergy). (05 Mar 2000) |
| immunological memory | <immunology> The systems responsible for the situation where reactions to a second or subsequent exposure to an antigen are more extensive than those seen on first exposure (but See immunological tolerance. The memory is best explained by clonal expansion and persistence of such clones following the first exposure to antigen. (18 Nov 1997) |
| immunological network | <immunology> The concept due to Jerne that the entire specific immune system within an animal is made up of a series of interacting molecules and cell surface receptors, based on the idea that every antibody combining site carries its own marker antigens or idiotypes and that these in turn may be recognised by another set of antibody combining sites and so on. (18 Nov 1997) |
| immunological paralysis | Lack of specific antibody production after exposure to large doses of the antigen; immunological paralysis disappears when the antigen is eliminated. See: immunologic tolerance. (05 Mar 2000) |
| immunological surveillance | <immunology> The hypothesis that lymphocyte traffic ensures that all or nearly all parts of the vertebrate body are surveyed by visiting lymphocytes in order to detect any altered self material, for example mutant cells. (18 Nov 1997) |
| immunological tolerance | <immunology> Specific unresponsiveness to antigen. Self tolerance is a process occurring normally early in life due to suppression of self reactive lymphocyte clones. Tolerance to foreign antigens can be induced in adult life by exposure to antigens under conditions in which specific clones are suppressed. Note that tolerance is not the same as immunological unresponsiveness, since the latter may be very non-specific as in immunodeficiency states. (18 Nov 1997) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |