| immune r. |
see under response.
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| immune r., primary |
the immune response occurring on the first exposure to an antigen. After a lag or latent period of from 3 to 14 days depending on the antigen, specific antibodies appear in the blood. There is a peak of IgM production lasting several days followed immediately by a peak of IgG production. Antibody production ceases after several weeks, but memory cells remain in circulation.
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| immune r., secondary |
the immune response occurring on the second and subsequent exposures to an antigen; compared to a primary response, the lag period is shorter, the peak antibody titer is higher and lasts longer, IgG production predominates, the antibodies produced have a higher affinity for the antigen, and a much smaller dose of the antigen is required to initiate the response. Called also anamnestic r. and booster r.
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