| idiotype |
the part of the variable region of an antibody that is unique for each antibody type.
출처: www.qimr.edu.au/qimr_glossary.html
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| idiotype |
The antigenic characteristic of the variable region of an immunoglobulin.
출처: www.sonoma.edu/users/t/thatcher/biol480/voc2.htm
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| idiotype–anti-idiotype n. |
a regulatory mechanism mounted in response to the unique or idiotypic determinants of lymphocytes or antibodies upon antigenic stimulation. Activation of a B cell results in a clone of plasma cells producing immunoglobulin of a single idiotype, which, because it was previously present in very small quantities, can be recognized as “nonself” and results in the production of anti-idiotypic antibodies directed against its idiotypic determinants. There can also be anti–anti-idiotypic antibodies directed against the second antibodies, antibodies directed against them, and so forth. These antibodies react with antigen receptors on B cells and T helper and suppressor cells, as well as with circulating antibodies, to enhance or suppress production of the initial antibody by various mechanisms.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| idiotype |
A classification of antibody molecules according to the antigenicity of the variable regions. Each idiotype is unique to a particular immunoglobulin raised to a particular antigen.
출처: aviscollege.com/tools/8000-terms.asp
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