| idiotype | The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts. (18 Nov 1997) |
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| idiotype antibody | <immunology> An antibody directed against the antigen specific part of the sequence of an antibody or T-cell receptor and thus recognise the binding sites of other antibodies. In principle an anti-idiotype antibody should inhibit a specific immune response and they are important to the regulation of the immune system. (13 Nov 1997) |
| idiotype autoantibody | <immunology> An autoantibody, the specificity of which is directed against one of one's own idiotypes. See: anti-idiotype antibody. Synonym: idiotype autoantibody. (05 Mar 2000) |
| anti-idiotype antibody | <immunology> An antibody directed against the antigen specific part of the sequence of an antibody or T-cell receptor and thus recognise the binding sites of other antibodies. In principle an anti-idiotype antibody should inhibit a specific immune response and they are important to the regulation of the immune system. (13 Nov 1997) |
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| anti-idiotype autoantibody | <immunology> An autoantibody, the specificity of which is directed against one of one's own idiotypes. See: anti-idiotype antibody. Synonym: idiotype autoantibody. (05 Mar 2000) |