| hypoxanthine |
6-oxypurine, a purine base formed as an intermediate in the degradation of purines and purine nucleosides to uric acid and in the salvage of free purines. It is found in some transfer RNA molecules and occurs complexed with ribose as the nucleoside inosine.
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| hypoxanthine phosphoribosyltransferase |
[EC 2.4.2.8] an enzyme of the transferase class that catalyzes the phosphorylation of hypoxanthine or guanine to its corresponding nucleoside monophosphate, a salvage mechanism for recovery of preformed purines, especially in the central nervous system. Absence of enzyme activity, an X-linked trait, results in Lesch-Nyhan syndrome; partially decreased enzyme activity results in hyperuricemia and severe gouty arthritis, but the neurologic sequelae of Lesch-Nyhan syndrome do not occur. Called also hypoxanthine-guanine phosphoribosyltransferase.
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| hypoxanthine t. |
see Kossel's t.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| hypoxanthine-guanine phosphoribosyltransferase |
hypoxanthine phosphoribosyltransferase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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