| hypoglycins | Methylene cyclopropyl alanine and congeners isolated from the unripe edible fruit of the akee plant (blighia sapida); hypoglycin b is the gamma-glutamyl congener of hypoglycin a; they are very toxic and teratogenic, causing a fall in blood glucose due to the interference of fatty acid and leucine metabolism which leads to vomiting, liver damage, convulsions and death; the syndrome is called jamaican vomiting sickness. (12 Dec 1998) |
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