| hyperimmunoglobulinemia D s. |
a periodic fever inherited as an autosomal recessive trait, caused by mutations in the gene for mevalonate kinase and having onset usually before one year of age. It is characterized by attacks of high fever preceded by chills, occurring at intervals of approximately 4–8 weeks and lasting 4–6 days, often accompanied by headache, arthritis and arthralgia, erythematous lesions, and hepatosplenomegaly; serum IgD levels are continuously high. Called also Dutch-type periodic fever.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
|---|