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hyperacute rejection The immediate killing (as soon as blood flows through vessels) of a transplanted organ, seen to occur in a patient who has preformed antibodies to the donor flowing in his or her blood stream.
Ãâó: www.llu.edu/ihi/def.html
hyperacute extremely acute.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
hyperacute r. graft rejection occurring immediately after transplantation and resulting from the presence of preformed, circulating cytotoxic antibodies against antigens (often non-HLA antigens) on the graft. Antigen-antibody complexes on vascular endothelium initiate an Arthus-type reaction (type III reaction) in which complement activation results in infiltration by neutrophils, endothelial injury, and occlusion of capillaries with fibrin-platelet thrombi; adequate blood flow to the graft is never established.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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