| hydroxymethyl and formyl transferases | <enzyme> Enzymes that catalyze the transfer of hydroxymethyl or formyl groups. Registry number: EC 2.1.2 (12 Dec 1998) |
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| hydroxymethylbilane synthase | <enzyme> An enzyme that catalyses the formation of hydroxymethylbilane from four molecules of porphobilinogen. Chemical name: Porphobilinogen ammonia-lyase (polymerizing) Registry number: EC 4.3.1.8 (12 Dec 1998) |
| hydroxymethyldeoxyuridinemonophosphate kinase | <enzyme> An aspect of nucleoside monophosphate kinase EC 2.7.4.4 Registry number: EC 2.7.4.- Synonym: hmdump kinase, hydroxymethyldeoxyuridine monophosphate kinase (26 Jun 1999) |
| hydroxymethyldihydropterin pyrophosphokinase | <enzyme> Convets 6-hydroxymethyl-7,8-dihydropterin and ATP to 6-hydroxymethyl-7,8-dihydropterin pyrophosphate and AMP Registry number: EC 2.7.6.- Synonym: suld gene product (26 Jun 1999) |
| hydroxymethylglutaryl CoA reductases | <enzyme> In the biosynthesis of cholesterol, these enzymes catalyze the reduction of one of the carboxyl groups of beta-hydroxy, beta-methylglutaryl CoA to yield mevalonic acid.4 requires NADP, EC 1.1.1.88 requires NAD. Chemical name: (S)-Mevalonate:NAD+ oxidoreductase (CoA-acylating) Registry number: EC 1.1.1.88 (12 Dec 1998) |
| hydroxymethylglutaryl-CoA reductase inhibitors | Compounds that inhibit hmg-CoA reductases. They have been shown to directly lower cholesterol synthesis. (12 Dec 1998) |
| hydroxymethylglutaryl-CoA synthase | <enzyme> An enzyme that catalyses the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. Chemical name: (S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) Registry number: EC 4.1.3.5 (12 Dec 1998) |
| hydroxymethylgutaryl-CoA hydrolase | <enzyme> May be important in regulating mammalian cholesterol synthesis Registry number: EC 3.1.2.5 Synonym: beta-hydroxy-beta-methylglutaryl coenzyme a hydrolase, beta-hydroxy-beta-methylglutaryl coenzyme a deacylase (26 Jun 1999) |
| hydroxymethylpyrimidine kinase | <enzyme> Found in E coli; catalyses th phosphorylation of 4-amino-5-hydroxymethyl-2-methylpyrimidine to 4-amino-5-phosphomethyl-2-methylpyrimidine in the presence of ATP Registry number: EC 2.7.1.49 (26 Jun 1999) |
| hydroxymethyluracil DNA glycosylase | <enzyme> Functions to eliminate hydroxymethyluracil from oxidatively damaged DNA Registry number: EC 3.2.2.- Synonym: hmu DNA glycosylase (26 Jun 1999) |
| alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase | <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus alpha-hydroxymethyl-succinic monoaldehyde Registry number: EC 3.5.1.- Synonym: compound b hydrolase (26 Jun 1999) |
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| tris(hydroxymethyl)aminomethane | <chemical> An organic amine proton acceptor. It is used in the synthesis of surface-active agent and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, is a biological buffer, and is used as an alkaliser. Pharmacological action: buffers, excipient. Chemical name: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)- (12 Dec 1998) |
| tris(hydroxymethyl)methylamine | <chemical> An organic amine proton acceptor. It is used in the synthesis of surface-active agent and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, is a biological buffer, and is used as an alkaliser. Pharmacological action: buffers, excipient. Chemical name: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)- (12 Dec 1998) |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-7,8-dihydropteroate synthase | <chemical> Bifunctional enzyme involved in folate biosynthesis in plants; genbank y08611 (pisum sativum) Synonym: hppk-dhps, pppk-dhps, hydroxymethyldihydropterin-pyrophosphokinase-dihydropteroate synthase (26 Jun 1999) |