| radiation chimera | An organism whose body contains cell populations of different genotypes as a result of the injection of foreign cells into it after it has received sufficient ionizing radiation to destroy the mature host cells which would otherwise reject the injected cells. (12 Dec 1998) |
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| chimera | <cell biology> Organism composed of two genetically distinct types of cells. Can be formed by the fusion of two early blastula stage embryos or by the reconstitution of the bone marrow in an irradiated recipient or by somatic segregation. (05 Jan 1998) |
| transplantation chimera | An organism that, as a result of transplantation of donor genetic material, consists of two or more cell lines descended from at least two zygotes. This state results in the induction of donor-specific transplantation tolerance. (12 Dec 1998) |
| homologous | Corresponding in structure, position, origin, etc., such as the feathers of a bird and the scales of a fish, the antigen and its specific antibody, the allelic chromosomes. Compare: analogous. Origin: Gr. Homologos = agreeing, correspondent (18 Nov 1997) |
| homologous antigen | <immunology> A homologous antigen is one which will attract and react with a specific antibody. (09 Oct 1997) |
| homologous antiserum | An antiserum in which there is complete correspondence between the content of antibodies and the antigenic material used for producing the antiserum. (05 Mar 2000) |
| homologous chromosome | <genetics> A pair of chromosomes containing the same linear gene sequences, each derived from one parent. The chromosomes tend to pair or synapse during mitosis. (14 Oct 1997) |
| homologous chromosomes | A pair of chromosomes containing the same gene sequences, each derived from one parent. (12 Dec 1998) |
| homologous desensitization | Loss of sensitivity only to the class of agonist used to desensitise the tissue. (05 Mar 2000) |
| homologous graft | <haematology> Grafts between two or more individuals allogeneic at one or more loci (usually with reference to histocompatibility loci). As opposed to autograft and xenograft. (18 Nov 1997) |
| homologous proteins | <molecular biology> Proteins that look similar and work in similar ways in different species. (09 Oct 1997) |
| homologous recombination | <molecular biology> Genetic recombination involving exchange of homologous loci. Important technique in the generation of null alleles (knockouts) in transgenic mice. (18 Nov 1997) |
| homologous series | A series of organic compounds, the succeeding members of which differ from each other by the radical CH2 (as in the fatty series). (05 Mar 2000) |
| homologous serotype | An antibody that was induced by a particular antigen and reacts with that antigen. (05 Mar 2000) |
| homologous serum jaundice | An obsolete term for viral hepatitis type B. (05 Mar 2000) |