| holo- | Whole, entire, complete. Origin: G. Holos (05 Mar 2000) |
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| holo-ACP synthase | <enzyme> An enzyme catalyzing transfer of the 4'-phosphopantetheinyl residue from CoA to a serine of apo-ACP (acyl carrier protein) to form holo-ACP, releasing adenosine 3',5'-bisphosphate; a required step if fatty acid biosynthesis is to function. (05 Mar 2000) |
| holoacardius | A separate, grossly defective twin lacking a heart of its own, its blood supply being dependent on a shunt from the placental circulation of a more nearly normal twin; a placental parasitic twin or omphalosite. Compare: acardius. Origin: holo-+ G. A-priv. + kardia, heart (05 Mar 2000) |
| holoacardius acephalus | A holoacardius also lacking a head. (05 Mar 2000) |
| holoacardius amorphus | A holoacardius in which the body of the parasite is represented by only a shapeless mass. See: anideus. (05 Mar 2000) |
| holoacrania | A congenital skull defect in which bones of the vault are absent. Origin: holo-+ G. A-priv. + kranion, skull (05 Mar 2000) |
| holoanencephaly | Complete absence of cranium and brain. Origin: holo-+ G. An-priv. + enkephalos, brain (05 Mar 2000) |
| holoblast | <biology> An ovum composed entirely of germinal matter. See Meroblast. Source: Websters Dictionary (01 Mar 1998) |
| holoblastic | <biology> Undergoing complete segmentation; composed entirely of germinal matter, the whole of the yolk undergoing fission; opposed to meroblastic. Source: Websters Dictionary (01 Mar 1998) |
| holoblastic cleavage | Cleavage in which the blastomeres are completely separated; the entire egg participates in cell division. Synonym: complete cleavage, total cleavage. (05 Mar 2000) |
| holocarboxylase synthetase | One of several enzymes that biotinylate other proteins (e.g., carboxylases); a deficiency of holocarboxylase synthetase will result in organic acidemia. (05 Mar 2000) |
| holocaust | A massive slaughter, especially the systematic mass extermination of european jews in nazi concentration camps prior to and during world war II. (12 Dec 1998) |
| holocephali | <zoology> An order of elasmobranch fishes, including, among living species, only the chimaeras. Synonym: Holocephala. See Chimaera; also Illustration in Appendix. Origin: NL, from Gr. "olos whole + head. Source: Websters Dictionary (01 Mar 1998) |
| holocephalic | Denoting a foetus with a complete head but having deficiencies in other body parts. Origin: holo-+ G. Kephale, head (05 Mar 2000) |
| holocord | Relating to the entire spinal cord, extending from the cervico-medullary junction to the conus medullaris. (05 Mar 2000) |