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HDAC 1/histone deacetylase
AHA Anti-histone antibodies
H1 Histone 1
HAT Histone acetyl transferase
NHP non histone proteins
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    ¸¹Àº ¿°±â¸¦ °¡Áö¸ç ¹°¿¡ °¡¿ë, ¹±Àº ¾Ï¸ð´Ï¾Æ¿¡ ºÒ¿ëÀÎ ´Ü¼øÇÑ ´Ü¹éÁú. ¾î¶² °ÍÀº ºÐ¸íÈ÷ µ¶¼ºÀÌ ÀÖÀ¸¸ç ´Ù·®ÀÇ ÀÎÀ» ÇÔÀ¯ÇÑ´Ù. ÇÙ»ê°ú °áÇÕÇÏ¿© ´ºÅ¬·¹¿ÀÈ÷½ºÅæÀ» Çü¼ºÇÏ¸ç ¿°»öÁúÀÇ DNA¿Í °ü°è ÀÖ´Ù. È÷½ºÅæ ó¸®ÇÑ Ç÷¾×Àº ÀÀ°íÇÏ±â ¾î·Æ°Ô º¯È­ÇÑ´Ù. È÷½ºÅæÀº ¹éÇ÷º´À̳ª ¹ß¿­ »óÅ ȯÀÚÀÇ ¿ÀÁÜ¿¡¼­ °ËÃâµÈ´Ù.
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histone <molecular biology> Protein found in the nuclei of all eukaryotic cells where they are complexed to DNA in chromatin and chromosomes. They are of relatively low molecular weight and are basic, having a very high arginine/lysine content. They are highly conserved and can be grouped into five major classes. Two copies of H2A, H2B, H3 and H4 bind to about 200 base pairs of DNA to form the repeating structure of chromatin, the nucleosome, with H1 binding to the linker sequence. They may act as non-specific repressors of gene transcription.
(18 Nov 1997)
histone bases The alpha-amino acids arginine, histidine, and lysine, which are basic by virtue of the presence in the side chains of a guanidine, imidazole, and amine group, respectively; the term "hexone" is a misnomer since histidine does not have six carbons.
(05 Mar 2000)
histone deacetylase <enzyme> Hydrolyzes n-acetyl groups on histones.
Registry number: EC 3.5.1.-
(12 Dec 1998)
histone gene A histone gene is any gene which codes for histone proteins. (Histones help compact DNA so that it will fit into an eukaryotic cells nucleus).
(09 Oct 1997)
histone h2b kinase <enzyme> 96 kD serine kinase from xenopus that phosphorylates histone h2b; a component or target of the raf-mek-erk pathway
Registry number: EC 2.7.1.-
Synonym: p96(h2bk)
(26 Jun 1999)
histone-lysine n-methyltransferase <enzyme> An enzyme that catalyses the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine.
Chemical name: S-Adenosyl-L-methionine:histone-L-lysine N(6)-methyltransferase
Registry number: EC 2.1.1.43
(12 Dec 1998)
histonectomy Synonym: periarterial sympathectomy.
Origin: histo-+ G. Ektome, excision
(05 Mar 2000)
histones Proteins associated with DNA in chromosomes.
(12 Dec 1998)
histoneurology The microscopic anatomy of the nervous system.
Synonym: histoneurology.
(05 Mar 2000)
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ADP ribose-histone hydrolase <enzyme> Splits bond between ADP ribose and histone
Registry number: EC 4.2.99.-
Synonym: ADP-ribosyl histone splitting enzyme, ADP-ribosyl protein lyase
(26 Jun 1999)
calcium-calmodulin-activated histone 3 arginine kinase <enzyme> From nuclear extracts of dividing and quiescent rat heart endothelial cells; represents a new class of ca-cam-dependent kinases which phosphorylate arg
Registry number: EC 2.7.10.-
Synonym: ca(2+)-calmodulin-activated histone 3 arg kinase, ca-cam h3 kinase
(26 Jun 1999)
chromosomal proteins, non-histone Nucleoproteins which in contrast to histones are acid insoluble. They are involved in chromosomal functions; e.g. They bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Histone Acetyltransferases - »õâ Enzymes that catalyze acyl group transfer from ACETYL-CoA to HISTONES forming CoA and acetyl-histones.
    Synonyms : Histone Acetylase, Histone Acetyltransferase, Acetylase, Histone, Acetyltransferase, Histone, Acetyltransferases, Histone
  • Histone Code - »õâ The specific patterns of POST-TRANSLATIONAL PROTEIN MODIFICATION of HISTONES, i.e. histone ACETYLATION; METHYLATION; PHOSPHORYLATION; and ubiquitination, at specific amino acid residues, that are involved in assembly, maintenance, and modification of different chromatin structural states, such as EUCHROMATIN and HETEROCHROMATIN.
    Synonyms : Code, Histone
  • Histone Deacetylases - »õâ Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. Some of these belong to the SIRTUINS protein family.
    Synonyms : HDAC Proteins, Histone Deacetylase, Deacetylase, Histone, Deacetylases, Histone, Proteins, HDAC
  • Histone-Lysine N-Methyltransferase - »õâ An enzyme that catalyzes the methylation of the epsilon-amino group of lysine residues in proteins to yield epsilon mono-, di-, and trimethyllysine. EC 2.1.1.43.
    Synonyms : Histone-Lysine Methyltransferase, Histone Lysine Methyltransferase, Histone Lysine N Methyltransferase, Methyltransferase, Histone-Lysine, Methyltransferase, Protein Lysine, N-Methyltransferase, Histone-Lysine
  • Histones - »õâ Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
    Synonyms : Histone, Histone H1, Histone H1(s), Histone H2a, Histone H2b, Histone H3, Histone H3.3, Histone H4, Histone H5, Histone H7
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histone a simple protein containing mainly basic amino acids; present in cell nuclei in association with nucleic acids
Ãâó: wordnet.princeton.edu/perl/webwn
histone A type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes.
Ãâó: www.stjude.org/glossary
histone A tiny protein made from around 100 amino acids, and creates histon cores, which attaches with DNA and forms a solid complex called cromatin.
Ãâó: library.thinkquest.org/28920/eng/wordlist.html
histone One of a class of basic proteins that are complexed with DNA in chromosomes and that play a major role in determining the structure of eukaryotic nuclear chromosomes.
Ãâó: www.modernhumanorigins.com/h.html
histone A type of basic protein that forms the unit around which DNA is coiled in the nucleosomes of eukaryotic chromosomes. Arginine and lysine rich basic proteins making up a substantial portion of eukaryotic nucleoprotein.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/gh.htm
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