histocompatibility antigen : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 3 페이지: 1

Histocompatibility Antigens - 새창 A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection.
Synonyms : Antigens, Transplantation, Histocompatibility Antigen, LD Antigens, SD Antigens, Antigen, Histocompatibility, Antigens, Histocompatibility, Antigens, LD, Antigens, SD
Histocompatibility Antigens Class I - 새창 Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-A; HLA-B and HLA-C antigens. In mice, three genes named K, D, and L on chromosome 17 code for the H-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders.
Synonyms : Class I Histocompatibility Antigens, Class I Human Antigens, Class I Major Histocompatibility Antigens, Human Class I Antigens, Antigens, Class I, I Antigens, Class
Histocompatibility Antigens Class II - 새창 Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.
Synonyms : Class II Antigen, Class II Histocompatibility Antigens, Class II Major Histocompatibility Antigens, I-A Antigen, I-A-Antigen, IA Antigen, Antigen, Class II, Antigen, I-A, Antigen, IA, Antigens, Class II, Antigens, Ia, Antigens, Ia-Like, Antigens, Immune-Associated