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hexosebisphosphatase <biochemistry> This key intermediate in glycolysis and gluconeogenesis (a hexose diphosphate) was discovered by Arthur Harden and William Young in 1905.
In the third step of glycolysis, fructose 6-phosphate and ATP are converted to fructose 1,6-bisphosphate and ADP with the aid of phosphofructokinase. In step 4, fructose 1,6 bisphosphate (with the aid of aldolase) is cleaved into duhydroxyacetone phosphate and glyceraldehyde 3-phosphate.
Synonym: hexosebisphosphatase, hexosediphosphatase.
(08 Mar 2000)
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