| HMP Shunt | Hexose Mono-Phosphate Shunt |
|---|---|
| HDP | hexose diphosphate; high-density polyethylene; hydrogen diphosphonate; hydroxydimethylpyrimidine |
| HMP | hexose monophosphate pathway; hot moist packs |
| HMPS | hexose monophosphate shunt |
| HMS | hexose monophosphate shunt; hypermobility syndrome |
| 2-5A synthetase | 2', 5'-oligoadenylate synthetase |
|---|---|
| HMP | Hexose monophosphate |
| HMP | Hexose monophosphate pathway |
| HMPS | Hexose monophosphate shunt |
| HMS | Hexose-monophosphate shunt |
| hexose phosphate synthetase | <enzyme> Ribulosephosphate formaldehyde gives d-erythro-l-glycero-3-hexulose Registry number: EC 4.1.2.- Synonym: 3-hexulose phosphate synthase, d-arabino-3-hexulose 6-phosphate formaldehyde-lyase, 3-hexulosephosphate synthase, d-arabino-3-hexulose-6-phosphate-lysase, hexulose-6-phosphate synthase, hump synthase (26 Jun 1999) |
|---|
| hexose-1-phosphate uridylyltransferase | <enzyme> An enzyme that catalyses the transfer of ump from udpglucose to galactose 1-phosphate, forming udpgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of galactosaemia. Chemical name: UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase Registry number: EC 2.7.7.12 (12 Dec 1998) |
|---|---|
| udpglucose-hexose-1-phosphate uridylyltransferase | <enzyme> An enzyme that catalyses the transfer of ump from udpglucose to galactose 1-phosphate, forming udpgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of galactosaemia. Chemical name: UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase Registry number: EC 2.7.7.12 (12 Dec 1998) |
| utp-hexose-1-phosphate uridylyltransferase | <enzyme> An enzyme that catalyses the synthesis of udpgalactose from utp and galactose-1-phosphate. It is present in low levels in foetal and infant liver, but increases with age, thereby enabling galactosaemic infants who survive to develop the capacity to metabolise galactose. Chemical name: UTP:alpha-D-hexose-1-phosphate uridylyltransferase Registry number: EC 2.7.7.10 (12 Dec 1998) |
| hexose | Monosaccharide containing six carbon atoms, for example glucose, galactose, mannose. (18 Nov 1997) |
| hexose monophosphate pathway | <biochemistry> A pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final one being an oxidative decarboxylation to form a pentose phosphate. Diverges from this when glucose-6-phosphate is oxidized to ribose 5 phosphate by the enzyme glucose-6 phosphate dehydrogenase. This step reduces NADP to NADPH, generating a source of reducing power in cells for use in reductive biosyntheses. In plants, part of the pathway functions in the formation of hexoses from carbon dioxide in photosynthesis. Also important as source of pentoses, for example for nucleic acid biosynthesis. This pathway is the main metabolic pathway in neutrophils, congenital deficiency in the pathway produces sensitivity to infection. Alternative metabolic route to Embden Meyerhof pathway for breakdown of glucose. (18 Nov 1997) |
| hexose monophosphate shunt | The main metabolic pathway in activated neutrophils, rendering them relatively insensitive to inhibitors of oxidative phosphorylation. Congenital deficiency of the first enzyme in the shunt, glucose 6 phosphate dehydrogenase, produces a sensitivity to infection similar to that seen in chronic granulomatous disease. (18 Nov 1997) |
| hexose monphosphate pathway | A metabolic pathway present in a wide range of prokaryotic and eukaryotic microorganisms as well as in plants and animals, it involves the oxidative decarboxylation of glucose-6-phosphate, via 6 phosphogluconate, to ribulose 5-phosphate, followed by a series of reversible, non-oxidative interconversions whereby hexose and triose phosphates are formed from pentose phosphates. (09 Oct 1997) |
| hexose phosphatase | <enzyme> May be an aspect of acid phosphatase, EC 3.1.3.2 Registry number: EC 3.1.3.- (26 Jun 1999) |
| bis(monoacylglycero)phosphate synthetase | <enzyme> Converts phosphatidylglycerol, 1-acyl- or 2-acyllysophosphatidylglycerol to bis(monoacylglycero)phosphate Registry number: EC 2.3.1.- (26 Jun 1999) |
| carbamoyl phosphate synthetase | A phosphotransferase catalyzing the formation of carbamoyl phosphate. There are two significant isozymes. Carbomoyl phosphate synthetase I is a mitochondrial enzyme that catalyses the reaction of 2ATP, NH3, CO2, and H2O to carbamoyl phosphate, 2ADP, and Pi. It is activated by N-acetylglutamate and participates in urea biosynthesis. A deficiency of carbamoyl phosphate synthetase I can result in hyperammonaemia. Carbamoyl phosphate synthetase II is a cytosolic enzyme that, under physiological conditions, uses l-glutamine as the nitrogen source (producing l-glutamate) instead of NH3, is not activated by N-acetylglutamate, and is found in pyrimidine biosynthesis. (05 Mar 2000) |
| N-(5-amino-1-ribosyl-4-imidazolylcarbonyl)-L-aspartic acid 5'-phosphate synthetase | <enzyme> 5-amino-1-ribosyl-4-imidazole carboxylic acid 5'-phosphate (carboxy-air), ATP and aspartate yield n(5-amino-4-imidazolylcarbonyl)-l-aspartic acid 5'-phosphate(succino-aicar), ADP and p Registry number: EC 6.3.4.- (26 Jun 1999) |
| UDPacetylglucosamine-dolichyl-phosphate acetylglucosamine-1-phosphate transferase | <enzyme> Transfers n-acetylglucosamine 1-phosphate from udp-n-acetylglucosamine to dolichyl phosphate, forming n-acetylglucosaminylpyrophosphoryldolichol Chemical name: udp-glcnac-dolichyl-phosphate glcnac-1-phosphate transerase Registry number: EC 2.7.8.15 Synonym: n-acetylglucosamine-1-phosphate transferase, dol-p-p-glcnac synthase, dolichol pathway enzyme I, udp-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphate transferase, glcnac-dp-1-phosphotransferase, udp-n-acetyl-d-glucosamine-dolichyl-phosphate n-acetyl-d-glucosaminephosphotransferase, dolichol-p-dependent n-acetylglucosamine-1-phosphate transferase, alg7 gene product (26 Jun 1999) |
| UDP-GlcNAc-undecaprenyl phosphate N-acetylglucosaminyl 1-phosphate transferase | <enzyme> Catalyses transfer of n-acetylglucosamine 1-phosphate from udp-glcnac to undecaprenyl phosphate Registry number: EC 2.7.8.- Synonym: glcnac-p-p-und synthase, gpt enzyme (26 Jun 1999) |
| acetoacetyl-CoA synthetase | <enzyme> Catalyses the conversion of acetoacetate and CoA in the presence of ATP to yield AMP, pyrophosphate and acetoacetyl-CoA; the latter is the first intermediate in cholesterogenesis; also acts more slowly on l-3-hydroxybutanoate Registry number: EC 6.2.1.16 Synonym: acetoacetyl-CoA ligase, acetoacetate-CoA ligase, acetoacetyl-coenzyme a synthetase (26 Jun 1999) |
| acetyl-CoA synthetase | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
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