| TMP | thiamine monophosphate; thymidine monophosphate; thymidine-5'-monophosphate; thymolphthalein monopho... |
|---|---|
| HMP | hexose monophosphate pathway; hot moist packs |
| HMPS | hexose monophosphate shunt |
| HMS | hexose monophosphate shunt; hypermobility syndrome |
| dAMP | deoxyadenosine monophosphate; deoxyadenylate adenosine monophosphate |
| HMP | Hexose monophosphate |
|---|---|
| HMP | Hexose monophosphate pathway |
| HMPS | Hexose monophosphate shunt |
| HMS | Hexose-monophosphate shunt |
| cAMP | 2',5'-cyclic adenosine monophosphate |
| hexose monophosphate pathway | <biochemistry> A pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final one being an oxidative decarboxylation to form a pentose phosphate. Diverges from this when glucose-6-phosphate is oxidized to ribose 5 phosphate by the enzyme glucose-6 phosphate dehydrogenase. This step reduces NADP to NADPH, generating a source of reducing power in cells for use in reductive biosyntheses. In plants, part of the pathway functions in the formation of hexoses from carbon dioxide in photosynthesis. Also important as source of pentoses, for example for nucleic acid biosynthesis. This pathway is the main metabolic pathway in neutrophils, congenital deficiency in the pathway produces sensitivity to infection. Alternative metabolic route to Embden Meyerhof pathway for breakdown of glucose. (18 Nov 1997) |
|---|---|
| hexose monophosphate shunt | The main metabolic pathway in activated neutrophils, rendering them relatively insensitive to inhibitors of oxidative phosphorylation. Congenital deficiency of the first enzyme in the shunt, glucose 6 phosphate dehydrogenase, produces a sensitivity to infection similar to that seen in chronic granulomatous disease. (18 Nov 1997) |
| hexose | Monosaccharide containing six carbon atoms, for example glucose, galactose, mannose. (18 Nov 1997) |
|---|---|
| hexose-1-phosphate uridylyltransferase | <enzyme> An enzyme that catalyses the transfer of ump from udpglucose to galactose 1-phosphate, forming udpgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of galactosaemia. Chemical name: UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase Registry number: EC 2.7.7.12 (12 Dec 1998) |
| hexose monphosphate pathway | A metabolic pathway present in a wide range of prokaryotic and eukaryotic microorganisms as well as in plants and animals, it involves the oxidative decarboxylation of glucose-6-phosphate, via 6 phosphogluconate, to ribulose 5-phosphate, followed by a series of reversible, non-oxidative interconversions whereby hexose and triose phosphates are formed from pentose phosphates. (09 Oct 1997) |
| hexose phosphatase | <enzyme> May be an aspect of acid phosphatase, EC 3.1.3.2 Registry number: EC 3.1.3.- (26 Jun 1999) |
| hexose phosphate synthetase | <enzyme> Ribulosephosphate formaldehyde gives d-erythro-l-glycero-3-hexulose Registry number: EC 4.1.2.- Synonym: 3-hexulose phosphate synthase, d-arabino-3-hexulose 6-phosphate formaldehyde-lyase, 3-hexulosephosphate synthase, d-arabino-3-hexulose-6-phosphate-lysase, hexulose-6-phosphate synthase, hump synthase (26 Jun 1999) |
| udpglucose-hexose-1-phosphate uridylyltransferase | <enzyme> An enzyme that catalyses the transfer of ump from udpglucose to galactose 1-phosphate, forming udpgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of galactosaemia. Chemical name: UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase Registry number: EC 2.7.7.12 (12 Dec 1998) |
| utp-hexose-1-phosphate uridylyltransferase | <enzyme> An enzyme that catalyses the synthesis of udpgalactose from utp and galactose-1-phosphate. It is present in low levels in foetal and infant liver, but increases with age, thereby enabling galactosaemic infants who survive to develop the capacity to metabolise galactose. Chemical name: UTP:alpha-D-hexose-1-phosphate uridylyltransferase Registry number: EC 2.7.7.10 (12 Dec 1998) |
| adenosine 3',5'-cyclic monophosphate | An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known. Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate. Acronym: cAMP (05 Mar 2000) |
| adenosine monophosphate | <chemical> Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Chemical name: 5'-Adenylic acid (12 Dec 1998) |
| pentose monophosphate shunt | <biochemistry> A pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final one being an oxidative decarboxylation to form a pentose phosphate. Diverges from this when glucose-6-phosphate is oxidized to ribose 5 phosphate by the enzyme glucose-6 phosphate dehydrogenase. This step reduces NADP to NADPH, generating a source of reducing power in cells for use in reductive biosyntheses. In plants, part of the pathway functions in the formation of hexoses from carbon dioxide in photosynthesis. Also important as source of pentoses, for example for nucleic acid biosynthesis. This pathway is the main metabolic pathway in neutrophils, congenital deficiency in the pathway produces sensitivity to infection. Alternative metabolic route to Embden Meyerhof pathway for breakdown of glucose. (18 Nov 1997) |
| guanosine 5'-monophosphate | A major component of ribonucleic acids. Synonym: guanine ribonucleotide, guanosine 5'-monophosphate. Guanylic acid reductase (GMP reductase), an enzyme that catalyses the reaction of GMP with NADPH producing IMP, NH3, and NADP+; a part of the purine salvage pathway. Guanylic acid synthetase (GMP synthetase), an enzyme catalyzing the reaction of l-glutamine, XMP, and ATP to produce GMP, l-glutamate, AMP, and pyrophosphate; a key step in purine biosynthesis. Acronym: GMP (05 Mar 2000) |
| guanosine monophosphate | A ribonucleotide which consists of the nitrogenous base guanine linked to the sugar ribose and which has a phosphate group attached to the 5th carbon atom of the ribose. (09 Oct 1997) |
| cyclic guanosine monophosphate | A cyclic version of the nucleotide guanosine monophosphate. It plays a role in communicating vision from the eyes to the brain. (09 Oct 1997) |
| cyclic uridine 3',5'-monophosphate | A cyclic nucleotide involved in metabolic regulation; inhibits the growth of some tumours. (05 Mar 2000) |
| cytidine monophosphate | A cytosine ribonucleotide (where the nitrogenous base cytosine is linked to the sugar ribose and a phosphate group) that helps make glycoproteins (a protein linked to a sugar or polysaccharide). (09 Oct 1997) |
| hexose monophosphate s. |
pentose phosphate pathway.
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