| hexamethonium | <chemical> A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool. Pharmacological action: antihypertensive agents, ganglionic blockers, nicotinic antagonists. Chemical name: 1,6-hexanediaminium, N,N,N,N',N',N'-hexamethyl- (12 Dec 1998) |
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| hexamethonium chloride | Hexamethylenebis(trimethylammonium chloride);a ganglionic blocking agent used in the treatment of hypertension, usually in combination with other hypotensive drugs; also used as the bromide and the tartrate. Synonym: hexamethone bromide, vegalysen. (05 Mar 2000) |
| hexamethonium compounds | <chemical> Compounds containing the hexamethylenebis(trimethylammonium) cation. Members of this group frequently act as antihypertensive agents and selective ganglionic blocking agents. Pharmacological action: antihypertensive agents, ganglionic blockers. (12 Dec 1998) |