| hepatitis B core antigen | <virology> (HBcAb, HBcAg), the antigen found in the core of the Dane particle (which is the complete virus) and also in hepatocyte nuclei in hepatitis B infections. (05 Mar 2000) |
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| hepatitis-associated antigen | A term used for the surface antigen of hepatitis B virus before its nature was established. See: hepatitis B surface antigen. (05 Mar 2000) |
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| hepatitis B antigen | Antigens of the virion of the hepatitis b virus or the dane particle, its surface, core and other associated antigens, like the hbe antigen. (12 Dec 1998) |
| hepatitis B e antigen | (HBeAb, HBe, HBeAg), an antigen, or group of antigen's, associated with hepatitis B infection and distinct from the surface antigen (HBsAg) and the core antigen (HBcAg); it is associated with the viral nucleocapsid. Its presence indicates that the virus is replicating and the individual is potentially infectious. (05 Mar 2000) |
| hepatitis B surface antigen | <virology> A serologic marker on the surface of the hepatitis B virus. The body will normally produce antibodies to hepatitis B surface antigen as part of the normal immune response to infection. It is the presence of antibodies to the hepatitis B surface antigen that are detected in a positive hepatitis B blood test. (27 Sep 1997) |
| atomic core | The nucleus plus the nonvalence electrons. (05 Mar 2000) |
| viral core proteins | Proteins found mainly in icosahedral DNA and RNA viruses. They consist of proteins directly associated with the nucleic acid inside the nucleocapsid. (12 Dec 1998) |
| central core disease | A congenital myopathy characterised by hypotonia, delay of motor development in infancy, and nonprogressive or slowly progressive muscle weakness; on biopsy the central core of muscle fibres stains abnormally, myofibrils are abnormally compact, and there is virtual absence of mitochondria and sarcoplasmic reticulum; histochemically, the cores are devoid of oxidative enzyme, phosphorylase, and ATPase activity; autosomal dominant inheritance, often subclinical. (05 Mar 2000) |
| central core disease of muscle | <neurology> One of the conditions that produces floppy baby syndrome. It causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). The disease is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1). Inheritance: autosomal dominant. (12 Dec 1998) |
| central transactional core | The reticular activating system of the brain. (05 Mar 2000) |
| muscle, central core disease of | One of the conditions that produces 'floppy baby' syndrome. Ccd causes hypotonia (inadequately toned muscles characterised by floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type i muscle fibres). Ccd is inherited as a dominant trait. The ccd gene is on chromosome 19 (and involves ryanodine receptor-1). (12 Dec 1998) |
| core | 1. The central mass of necrotic tissue in a boil. 2. A metal casting, usually with a post in the canal of a tooth root, designed to retain an artificial crown. 3. A sectional record, usually of plaster of Paris or one of its derivatives, of the relationships of parts, such as teeth, metallic restorations, or copings. Origin: L. Cor, heart 4. The pupil (of the eye). Origin: G. Kore, pupil (05 Mar 2000) |
| core biopsy | Removal (with a large needle) of a piece of a lump. The piece is sent to the lab to see if the lump is benign or malignant. (09 Oct 1997) |
| core II protein, ubiquinol-cytochrome c reductase | <chemical> Member of the mitochondrial-protein-processing family; protein found in subunits of ubiquinol-cytochrome c reductase; amino acid sequence given in first source Synonym: core II protein, uccreductase (26 Jun 1999) |
| core I protein, ubiquinol-cytochrome c reductase | <chemical> Member of the mitochondrial-protein-processing family; protein found in subunits of ubiquinol-cytochrome c reductase; amino acid sequence given in first source Synonym: core I protein, uccreductase (26 Jun 1999) |
| core particle | The group of eight histones (protein molecules which act like spools for DNA to wrap around so that it can be compacted to fit within the nucleus) in the middle of a nucleosome (which is the histone core particle plus the small segment of DNA wrapped around it). (09 Oct 1997) |