| HS | Haber syndrome; half strength; hamstring; hand surgery; Hartmann solution; head sling; healthy subje... |
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| HS-PG | heparan sulfate-proteoglycan |
| HS | Heparan Sulfate |
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| HS | Heparan sulphate |
| HSPG | Heparan sulphate proteoglycan |
| HS-GAG | heparan sulfate glycosaminoglycan |
| HBD | heparan-binding domain |
| heparan N-sulfatase | <enzyme> An enzyme that participates in the stepwise degradation of heparan sulfate; heparan N-sulfatase hydrolyzes the sulfate moiety attached to the amino group of the glucosamine residue of heparan sulfate; a deficiency of this enzyme is associated with mucopolysaccharidose IIIA (Sanfilippo's syndrome A). (05 Mar 2000) |
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| heparan sulfate | <chemical> Heparitin, sulfate. A glycosaminoglycan occurring in the liver, aorta, and lung. It has a structure similar to heparin, but there are more n-acetyl groups and fewer o- and n-sulfate groups. It is an accumulation product in several mucopolysaccharidoses. Chemical name: Heparitin, sulfate (12 Dec 1998) |
| heparan sulfate D-glucosaminyl 3-O-sulfotransferase | <enzyme> Involved in biosynthesis of heparan sulfate proteoglycans Registry number: EC 2.8.2.- Synonym: hsg 3-o-sulfotransferase (26 Jun 1999) |
| heparan sulfate proteoglycan | Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (12 Dec 1998) |
| heparan sulfate sulfatase | <enzyme> Probable defect in sanfilippo a syndrome Registry number: EC 3.1.6.- Synonym: heparan sulphatase (26 Jun 1999) |
| heparan sulfate-N-deacetylase-N-sulfotransferase | <enzyme> Catalyses both the n-deacetylation and the n-sulfation reactions that begin modification of heparan sulfate's oligosaccharide backbone Registry number: EC 2.8.2.- Synonym: hs-ndac-nst (26 Jun 1999) |
| heparan sulphate | Constituent of membrane associated proteoglycans. The heparan sulphate binding domain of NCAM is proposed to augment NCAM NCAM interactions, suggesting that cell cell bonds mediated by NCAM may involve interactions between multiple ligands. The putative heparin binding site on NCAM is a 28 aa peptide shown to bind both heparin and retinal cells, as well as to inhibit retinal cell adhesion to NCAM. This strengthens the argument that that this site contributes directly to NCAM mediated cell cell adhesion. (18 Nov 1997) |
| heparan-sulfate 2-sulfotransferase | <enzyme> An o-sulfotransferase that catalyses transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to l-iduronic acid at position 2 of heparan sulfate; genbank d88811 Registry number: EC 2.8.2.- Synonym: hs2st enzyme (26 Jun 1999) |
| heparanase | <enzyme> Tumour cell enzyme has endoglycosidase activity which degrades glycosaminoglycans into fragments of intermediate size Registry number: EC 3.2.1.- (26 Jun 1999) |
Synonyms : Proteoheparan Sulfate, Proteoglycan, Heparan Sulfate, Proteoglycans, Heparan Sulfate, Sulfate Proteoglycans, Heparan
| heparan N- |
a lysosomal enzyme of the hydrolase class that catalyzes the removal of sulfate from terminal N-sulfated glucosamine residues of heparan sulfate chains. Deficiency of the enzyme, an autosomal recessive trait, causes Sanfilippo's syndrome, type A. See also N-sulfoglucosamine sulfohydrolase.
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| heparan sulfate |
a glycosaminoglycan occurring in the cell membrane of most cells. It consists of repeating disaccharide units in specific linkage, each composed of a glucosamine residue linked to a uronic acid, either glucuronic acid or L-iduronic acid, which may be sulfated. The glucosamine residues frequently contain acetyl or sulfate group substituents. It is an accumulation product in several mucopolysaccharidoses.
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| heparan sulfate sulfamidase |
heparan N-sulfatase.
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| heparan-α-glucosaminide N- |
[EC 2.3.1.78] a lysosomal enzyme of the transferase class that catalyzes the acetylation of the amino groups of terminal desulfated glucosamine residues in heparan sulfate chains, a step in the degradation of heparan sulfate. Acetyl coenzyme A is the acetyl donor. Deficiency of the enzyme, an autosomal recessive trait, results in Sanfilippo's syndrome, type C. Called also acetyl CoA:α-glucosaminide N-acetyltransferase.
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